Fournier-Del Castillo C, Pérez-Jiménez A, García-Fernández M, García-Peñas J J, Villarejo-Ortega F J
Hospital Infantil Universitario Niño Jesús, Madrid, España.
Rev Neurol. 2010 Mar 3;50 Suppl 3:S49-57.
Neuropsychological assessment is included in the protocols for evaluation of epilepsy surgery candidates, providing information about the patient's cognitive dysfunctions, allowing for prediction of possible cognitive deficits derived from surgery and yielding objective measures of any post-surgical changes. Neuropsychological disturbances constitute an important co-morbidity of medically intractable epilepsy. An early epilepsy onset in infancy may lead to cognitive dysfunctions that are atypical in terms of brain localization, due to the inherent plasticity and reorganization processes of the immature brain. The analysis of the neuropsychological profiles of paediatric focal epilepsies is much more complex than in the adult population.
In this paper, we review the neuropsychological disturbances associated to focal epilepsies (posterior cortex, temporal and frontal epilepsies), stressing the point that there is a considerable lack of rigorous studies on the topic in the literature, in spite of this being an essential part of the presurgical work-up in epilepsy patients.
神经心理学评估包含在癫痫手术候选者的评估方案中，可提供有关患者认知功能障碍的信息，有助于预测手术可能导致的认知缺陷，并为术后的任何变化提供客观测量。神经心理障碍是药物难治性癫痫的一种重要合并症。婴儿期的早期癫痫发作可能会导致认知功能障碍，由于未成熟大脑固有的可塑性和重组过程，这种认知功能障碍在脑定位方面是非典型的。小儿局灶性癫痫的神经心理学特征分析比成人更为复杂。
在本文中，我们回顾了与局灶性癫痫（后皮质、颞叶和额叶癫痫）相关的神经心理障碍，强调尽管这是癫痫患者术前检查的重要组成部分，但文献中对该主题的严格研究相当匮乏。
