Arai N, Hara A, Umeda M, Shirai T
First Dept. of Internal Medicine, Toho University School of Medicine.
Rinsho Ketsueki. 1991 Jan;32(1):52-5.
This paper reports a rare case of extranodal non-Hodgkin's lymphoma localized at the ocular muscle, which achieved a long-term remission by combination chemotherapy and irradiation. A 41-year-old man visited the ophthalmology department of Toho University Hospital in December, 1982 because of right conjunctival injection and right exophthalmos which were first manifested in June. The patient was diagnosed as having non-Hodgkin's lymphoma (diffuse medium-sized cell type) by biopsy of the right medial rectal muscle, and was referred to our department on January 17, 1983. A series of examinations revealed that the disease had no invasion into any lymph nodes and other organs. After treatment with two courses of C-MOPP regimen and two courses of ACOP regimen, the patient achieved complete remission and was discharged on July 30. Subsequently he completed two courses of CHOP regimen followed by irradiation (46 Gy). Seven years and three months after the initiation of chemotherapy, the patient has been in a complete remission, requiring no treatment.
本文报告了1例罕见的结外非霍奇金淋巴瘤,病变局限于眼肌,经联合化疗及放疗后获得长期缓解。一名41岁男性因右眼结膜充血及右眼突出于1982年12月就诊于东邦大学医院眼科,上述症状于6月首次出现。经右内侧直肌活检,患者被诊断为非霍奇金淋巴瘤(弥漫性中等大小细胞型),并于1983年1月17日转入我科。一系列检查显示,该疾病未侵犯任何淋巴结及其他器官。经过两个疗程的C-MOPP方案及两个疗程的ACOP方案治疗后,患者达到完全缓解,并于7月30日出院。随后,他完成了两个疗程的CHOP方案治疗,之后接受放疗(46 Gy)。化疗开始7年零3个月后,患者一直处于完全缓解状态,无需治疗。