Goţia Stela, Russu Georgiana
Facultatea de Medicină, Clinica a II-a Pediatrie, Universitatea de Medicină si Farmacie "Gr.T. Popa" Iaşi.
Rev Med Chir Soc Med Nat Iasi. 2008 Jul-Sep;112(3):590-7.
Obesity has an increasing incidence throughout the world, inducing a complex and multisystemic pathology. The respiratory manifestations are: restrictive respiratory physiology, reduced respiratory compliance, altered ventilation/perfusion index, bronchial hyperresponsiveness. Increases in body mass index (BMI) are associated with increases in prevalence, incidence and severity of bronchial asthma. The mechanic effects of obesity remain important, but the adipocites have many influences by the hormones, leptines, cytokines and other proinflammatory agents.
肥胖在全球的发病率不断上升，引发了一种复杂的多系统病理状况。呼吸系统表现为：限制性呼吸生理、呼吸顺应性降低、通气/灌注指数改变、支气管高反应性。体重指数（BMI）的增加与支气管哮喘的患病率、发病率和严重程度增加相关。肥胖的机械性影响仍然很重要，但脂肪细胞受到激素、瘦素、细胞因子和其他促炎因子的多种影响。
