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性传播感染和艾滋病毒/艾滋病感染者的传染性信念:对艾滋病毒治疗即预防的影响。

Sexually transmitted infections and infectiousness beliefs among people living with HIV/AIDS: implications for HIV treatment as prevention.

机构信息

Department of Psychology, University of Connecticut, Storrs, Connecticut 06269, USA.

出版信息

HIV Med. 2010 Sep;11(8):502-9. doi: 10.1111/j.1468-1293.2009.00818.x. Epub 2010 Mar 1.

Abstract

OBJECTIVES

Sexually transmitted infections (STIs) significantly impact the health of people living with HIV/AIDS, increasing HIV infectiousness and therefore transmissibility. The current study examined STIs in a community sample of 490 HIV-positive men and women.

METHODS

Assessments were performed using confidential computerized interviews in a community research setting.

RESULTS

Fourteen per cent of the people living with HIV/AIDS in this study had been diagnosed with a new STI in a 6-month period. Individuals with a new STI had significantly more sexual partners in that time period, including non-HIV-positive partners. Participants who had contracted an STI were significantly more likely to have detectable viral loads and were less likely to know their viral load than participants who did not contract an STI. Multivariate analysis showed that believing an undetectable viral load leads to lower infectiousness was associated with contracting a new STI.

CONCLUSIONS

Individuals who believed that having an undetectable viral load reduces HIV transmission risks were more likely to be infectious because of STI coinfection. Programmes that aim to use HIV treatment for HIV prevention must address infectiousness beliefs and aggressively control STIs among people living with HIV/AIDS.

摘要

目的

性传播感染(STI)显著影响艾滋病毒/艾滋病感染者的健康,增加 HIV 的传染性和传播性。本研究在一个社区样本中对 490 名 HIV 阳性的男性和女性进行了 STI 检测。

方法

在社区研究环境中使用机密的计算机化访谈进行评估。

结果

在这项研究中,14%的艾滋病毒/艾滋病感染者在 6 个月内被诊断出患有新的 STI。在这段时间内,患有新的 STI 的人有更多的性伴侣,包括 HIV 阴性的伴侣。感染 STI 的参与者的病毒载量明显更高,而且他们不知道自己的病毒载量的可能性比没有感染 STI 的参与者更高。多变量分析表明,相信不可检测的病毒载量会降低传染性与感染新的 STI 有关。

结论

认为不可检测的病毒载量降低 HIV 传播风险的人,由于 STI 合并感染,更有可能具有传染性。旨在利用 HIV 治疗预防 HIV 的项目必须解决传染性信念,并积极控制 HIV 感染者中的 STI。

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How reliable is an undetectable viral load?病毒载量检测不出时,有多可靠?
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