Möller Fanny, Liska Jan, Lockowandt Ulf, Samuelsson Sten, Franco-Cereceda Anders
Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
J Card Surg. 2010 May;25(3):272-6. doi: 10.1111/j.1540-8191.2010.01014.x. Epub 2010 Feb 23.
Resternotomy during closed chest cardiopulmonary bypass in hypothermia with or without circulatory arrest has been the preferred method for cardiac reoperations with adherent structures to the sternum. Here, we report our experience with this method and the effects of omitting ventricular decompression during the cooling procedure.
Twenty reoperations were performed in 19 patients. In half (n = 10) of the procedures aortic regurgitation was present. Cardiopulmonary bypass was instituted in all patients before resternotomy, and the re-entry into the chest was performed either under hypothermic low-flow cardiopulmonary bypass or circulatory arrest. The reason for this choice of technique was adherent structures to the sternum posing a substantial risk for rupture during resternotomy in all patients.
Rupture upon re-entry into the chest occurred in five operations. No patient died due to re-entry injury. The overall hospital mortality was 15%. No differences in postoperative outcomes including heart failure, biochemical markers indicating myocardial damage, and three-month follow-up assessment of cardiac function were found between patients with aortic regurgitation and patients without aortic regurgitation.
Based on our experience, omitting ventricular decompression in resternotomy in hypothermia and arrested circulation or low-flow cardiopulmonary bypass can be safely used, and the presence of aortic regurgitation does not seem to influence the outcome.
在低温体外循环下进行胸骨切开再手术,无论有无循环停止,一直是胸骨粘连结构心脏再次手术的首选方法。在此,我们报告我们使用该方法的经验以及在降温过程中省略心室减压的效果。
对19例患者进行了20次再次手术。其中一半(n = 10)手术存在主动脉瓣反流。所有患者在胸骨切开再手术前均建立体外循环,再次开胸在低温低流量体外循环或循环停止下进行。选择该技术的原因是所有患者胸骨粘连结构在胸骨切开再手术期间有破裂的重大风险。
5例手术在再次开胸时发生破裂。无患者因再次开胸损伤死亡。总体医院死亡率为15%。在有主动脉瓣反流的患者和无主动脉瓣反流的患者之间,未发现包括心力衰竭、指示心肌损伤的生化标志物以及心脏功能的三个月随访评估等术后结果存在差异。
根据我们的经验,在低温及循环停止或低流量体外循环下进行胸骨切开再手术时省略心室减压可安全使用,且主动脉瓣反流的存在似乎不影响结果。