患者存在 IgM 副蛋白血症/早期瓦尔登斯特伦巨球蛋白血症时出现皮肤巨球蛋白血症沉积。
Cutaneous macroglobulinosis deposits in a patient with IgM paraproteinemia/incipient Waldenström macroglobulinemia.
机构信息
Dermatohistopathological Laboratory, Munich, Germany.
出版信息
J Dtsch Dermatol Ges. 2010 Dec;8(12):1000-3. doi: 10.1111/j.1610-0387.2010.07392.x.
Abstract
A 43-year-old healthy patient developed disseminated flat skin-colored to red-brown papules over a few months. These papules were the result of cutaneous IgM deposits representing the first symptom of a hitherto undiagnosed IgM paraproteinemia. This extremely rare skin manifestation of IgM paraproteinemia e. g. possibly incipient Waldenström macroglobulinemia should be included in the histopathological differential of eosinophilic dermal deposits.
摘要
一位 43 岁健康患者在数月内出现了散在的扁平肤色至红棕色丘疹。这些丘疹是皮肤 IgM 沉积的结果，代表了一种先前未诊断的 IgM 副蛋白血症的首发症状。IgM 副蛋白血症的这种极其罕见的皮肤表现，例如可能是初期的 Waldenström 巨球蛋白血症，应纳入嗜酸性真皮沉积的组织病理学鉴别诊断中。
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