Suppr超能文献

1188 例成年人的口腔主诉和刺激性唾液流率。

Oral complaints and stimulated salivary flow rate in 1188 adults.

机构信息

Department of Oral and Maxillofacial Sciences, Gifu University Graduate School of Medicine, Gifu, Japan.

出版信息

J Oral Pathol Med. 2010 May;39(5):407-19. doi: 10.1111/j.1600-0714.2009.00852.x. Epub 2010 Feb 28.

Abstract

BACKGROUND

Recently, oral sensory complaints (OSC) were proposed as a disease entity to represent idiopathic sensory disturbances of dry mouth, burning mouth, and taste disturbance, even though neither the status of OSC in the general population nor its underlying mechanism has yet been elucidated. Moreover, these three OSC-related complaints have not been assessed in combination by means of a visual analog scale (VAS) in a large-scale, community-dwelling population of a broad age range.

METHODS

In a 1188-member community-dwelling adult population, comprised of 373 males and 815 females, aged 20-90 years, the three OSC-related complaints and stimulated salivary flow rate (SSFR) were assessed by means of a VAS and modified Saxon test, respectively. Association of each complaint with age, gender, SSFR, and other complaints was analyzed.

RESULTS

Increases in both prevalence and intensity of subjective dry mouth and burning mouth were associated closely with decreasing SSFR. Even for taste disturbance, which may be affected less significantly by salivation status than the other two complaints, a significant association was suggested between decreasing SSFR and especially severe taste disturbance. However, these oral complaints were found in considerable prevalence even in the individuals with high SSFR. Often overlapping presentation of these complaints and a close association in intensity between the complaints to each other were also found.

CONCLUSIONS

Hyposalivation may be a significant and common etiology for the three oral complaints, although the considerable prevalence of complaints without hyposalivation suggests other etiologies, including those related to the OSC.

摘要

背景

最近,口腔感觉异常(OSC)被提出作为一种疾病实体,代表口干、口腔烧灼感和味觉障碍的特发性感觉障碍,尽管 OSC 在普通人群中的状况及其潜在机制尚未阐明。此外,这三种与 OSC 相关的投诉尚未通过视觉模拟量表(VAS)在广泛年龄范围内的大规模社区居住人群中进行联合评估。

方法

在一个由 373 名男性和 815 名女性组成的 1188 名社区居住成年人群中,年龄在 20-90 岁之间,通过 VAS 和改良的 Saxon 试验分别评估了三种与 OSC 相关的投诉和刺激性唾液流量(SSFR)。分析了每种投诉与年龄、性别、SSFR 和其他投诉的关联。

结果

主观口干和口腔烧灼感的发生率和强度增加与 SSFR 的降低密切相关。即使对于味觉障碍,其受唾液分泌状态的影响可能不如其他两种投诉那么显著,SSFR 降低与味觉障碍特别是严重程度之间也存在显著关联。然而,这些口腔投诉在具有高 SSFR 的个体中也有相当高的发生率。这些投诉的表现常常重叠,而且彼此之间的强度也密切相关。

结论

低唾液分泌可能是这三种口腔投诉的重要且常见的病因,尽管没有低唾液分泌的投诉相当高的发生率表明存在其他病因,包括与 OSC 相关的病因。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验