Institut National de la Recherche Scientifique-Institut Armand-Frappier, Laval, Quebec, Canada.
Emerg Infect Dis. 2010 Mar;16(3):561-4. doi: 10.3201/eid1603.090746.
Porcine plasma and factor VIII preparations were screened for parvovirus 4 (PARV)-like viruses. Although the prevalence of PARV4-like viruses in plasma samples was relatively low, viruses appeared to be concentrated during manufacture of factor VIII. PARV4-like viruses from human and porcine origins coevolved likewise with their hosts.
猪血浆和因子 VIII 制剂被筛选是否存在细小病毒 4(PARV)样病毒。虽然血浆样本中 PARV4 样病毒的流行率相对较低,但在因子 VIII 的生产过程中似乎存在病毒浓缩现象。源自人和猪的 PARV4 样病毒与宿主同样经历共同进化。