Baillif S, Hartmann D, Freney J, Kodjikian L
Département d'Ophtalmologie, Centre hospitalo-universitaire Saint Roch, Nice, France; Laboratoire "Réparation Tissulaire, Interactions Biologiques et Biomatériaux", UPSP 2007.03.135 RTI2B, Lyon, France.
J Fr Ophtalmol. 2010 Mar;33(3):210-21. doi: 10.1016/j.jfo.2010.01.016. Epub 2010 Mar 4.
Adhesion of bacteria to intraocular lenses is an important step in the pathogenesis of postoperative endophthalmitis. It can be described as a two-phase process including an initial, instantaneous, and reversible phase followed by a time-dependant and irreversible molecular and cellular phase. The binding of bacteria is affected by many factors including environmental factors such as medium composition, presence of proteins and flow conditions, the bacterial cell surface characteristics, and the material's surface properties. This article reviews all these factors affecting the adhesion of bacteria to intraocular lenses. A better understanding of these mechanisms would make it possible to reduce the bacterial adhesion process and thus could help decrease the incidence of postoperative endophthalmitis.
细菌与人工晶状体的黏附是术后眼内炎发病机制中的重要一步。它可被描述为一个两阶段过程，包括初始的、瞬时的、可逆阶段，随后是一个时间依赖性的、不可逆的分子和细胞阶段。细菌的黏附受许多因素影响，包括环境因素，如培养基成分、蛋白质的存在和流动条件、细菌细胞表面特征以及材料的表面特性。本文综述了所有这些影响细菌与人工晶状体黏附的因素。更好地理解这些机制将有可能减少细菌黏附过程，从而有助于降低术后眼内炎的发生率。
