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采采蝇种群遗传学如何有助于控制非洲锥虫病?

How can tsetse population genetics contribute to African trypanosomiasis control?

机构信息

Institut de Recherche pour le Développement (IRD)/Centre International de Recherche pour l'Elevage en zones Subhumides (CIRDES), IRD UMR 177, CIRDES 01 BP 454 Bobo-Dioulasso 01, Burkina Faso.

出版信息

Trends Parasitol. 2010 May;26(5):255-63. doi: 10.1016/j.pt.2010.02.006. Epub 2010 Mar 2.

DOI:10.1016/j.pt.2010.02.006
PMID:20202905
Abstract

In sub-Saharan Africa, tsetse transmitted Trypanosomiases have an enormous impact on human health and economic development. Both the World Health Organisation and African countries through the Pan African Tsetse and Trypanosomiasis Eradication Campaign (PATTEC) have recently asserted their determination to rid the sub-continent of these diseases, and it is increasingly recognised that vector control should play an important role. This review mainly focuses on population genetics of tsetse of the palpalis group, the main vectors of sleeping sickness, and reports recent results on tsetse population structure and on measures of gene flow between populations. Implications of these studies for large-scale tsetse control programmes being undertaken in West Africa are important, particularly regarding control strategies (suppression or eradication).

摘要

在撒哈拉以南非洲,采采蝇传播的锥虫病对人类健康和经济发展有巨大影响。世界卫生组织和非洲国家通过泛非采采蝇和锥虫病防治运动(PATTEC)最近都表示决心要在非洲大陆消灭这些疾病,人们越来越认识到,病媒控制应该发挥重要作用。本综述主要集中在传播昏睡病的主要媒介舌蝇属的种群遗传学上,并报告了有关舌蝇种群结构和种群间基因流动措施的最新结果。这些研究对正在西非开展的大规模采采蝇控制计划具有重要意义,特别是在控制策略(抑制或根除)方面。

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