Stroke. 2010 Apr;41(4):821-4. doi: 10.1161/STROKEAHA.109.574160. Epub 2010 Mar 4.
The purpose of our study was to investigate the effects of different doses of neuromuscular electrical stimulation (NMES) on upper-extremity function in acute stroke patients with severe motor deficit.
Sixty-six acute stroke patients were randomized to 3 groups: high NMES, low NMES, or control. The low-NMES group received 30 minutes of stimulation per day, and the high-NMES group received 60 minutes per day, for 4 weeks. The Fugl-Meyer Motor Assessment Scale, Action Research Arm Test, and Motor Activity Log were used to assess the patients at baseline, 4 weeks, and 12 weeks post baseline (follow-up).
Both NMES groups showed significant improvement on Fugl-Meyer Motor Assessment and Action Research Arm Test scales compared with the control group at week 4 and follow-up. The high-NMES group showed treatment effects similar to those of the low-NMES group.
Higher and lower doses of NMES led to similar improvements in motor function. A minimum of 10 hours of NMES in combination with regular rehabilitation may improve recovery of arm function in stroke patients during the acute stage.
本研究旨在探讨不同剂量的神经肌肉电刺激（NMES）对急性脑卒中伴严重运动功能障碍患者上肢功能的影响。
66 例急性脑卒中患者随机分为 3 组：高 NMES 组、低 NMES 组和对照组。低 NMES 组每天接受 30 分钟刺激，高 NMES 组每天接受 60 分钟刺激，持续 4 周。在基线、4 周和 12 周（随访）时，采用 Fugl-Meyer 运动评估量表、动作研究臂测试和运动活动日志评估患者。
与对照组相比，NMES 两组在第 4 周和随访时在 Fugl-Meyer 运动评估量表和动作研究臂测试量表上均有显著改善。高 NMES 组的治疗效果与低 NMES 组相似。
较高和较低剂量的 NMES 均导致运动功能的相似改善。急性脑卒中患者在常规康复治疗的基础上，至少 10 小时的 NMES 治疗可能会改善手臂功能的恢复。
