Department of Clinical Laboratory, National Hospital Organization Shikoku Cancer Center, 160 Kou, Minamiumemoto-machi, Matsuyama, Ehime, Japan.
Breast Cancer. 2011 Jan;18(1):33-6. doi: 10.1007/s12282-010-0199-4. Epub 2010 Mar 4.
Breast cancer screening by mammography (MMG) has recently increased in Japan. Suspicious lesions are therefore being detected more and more by MMG and the number of benign biopsies is increasing. It is thus important to examine which pathologically benign lesions were read as suspicious on MMG to reduce the number of biopsies in the case of benign breast lesions.
Of 299 category 3 or 4 lesions on MMG, 39 histologically benign lesions with calcification were reviewed and compared with the mammograms by a pathologist and a radiologist. The Japan Mammography Guidelines were used for MMG interpretation.
In mastopathy lesions, small round segmental calcifications and pleomorphic clustered calcifications were assessed as suspicious. The suspicious type of calcification in fibroadenoma was small round clustered. The calcifications in fibroadenoma may be seen as small round when the fibroadenoma is rather young, and assessed as suspicious.
Some types of calcifications in mastopathy and fibroadenoma were assessed as borderline by MMG. We should therefore collect data from more benign cases with suspicious calcifications on MMG and elucidate the diagnostic criteria in MMG findings of such calcifications.
在日本，乳腺 X 线摄影（MMG）筛查最近有所增加。因此，MMG 检测到的可疑病变越来越多，良性活检的数量也在增加。因此，重要的是要检查在 MMG 上读为可疑的哪些病理良性病变，以减少良性乳腺病变的活检数量。
对 299 个 MMG 类别 3 或 4 病变中的 39 个有钙化的组织学良性病变进行了回顾性分析，并由病理学家和放射科医生对 MMG 进行了比较。MMG 解释采用日本乳腺 X 线摄影指南。
在乳腺病病变中，小圆段状钙化和多形簇状钙化被评估为可疑。纤维腺瘤中的可疑钙化类型为小圆簇状。纤维腺瘤中的钙化在纤维腺瘤较年轻时可能表现为小圆点状，被评估为可疑。
乳腺病和纤维腺瘤中的某些类型的钙化在 MMG 中被评估为边界性。因此，我们应该从更多具有 MMG 可疑钙化的良性病例中收集数据，并阐明这些钙化的 MMG 结果的诊断标准。
