Biomedical Optics Research Laboratory, Department of Medical Physics and Bioengineering, University College London, London, UK.
Adv Exp Med Biol. 2010;662:183-9. doi: 10.1007/978-1-4419-1241-1_26.
A new approach to measure muscle oxygen saturation (SmO(2)) using near infrared spectroscopy (NIRS) has been proposed in this paper. This approach exploits the cyclic NIRS signals seen during exercise which are often regarded as "movement artefacts". This new measure, which we term the "cyclic SmO(2)", has the potential to be less affected by the myoglobin which is traditionally believed to be indistinguishable from haemoglobin using NIRS techniques. The cyclic SmO(2) also has fewer assumptions than the conventional SmO(2) measured using time, phase and spatially resolved spectroscopy methods. In a cycling exercise study, NIRS measurements were made over the Vastus lateralis muscle of 11 subjects. In a light exercise protocol, the group mean of the conventional SmO(2) was 51.7 +/- 4.3% and that of the cyclic SmO(2) was 56.0 +/- 3.9%. It was immediately followed by a hard exercise protocol and the group mean of the conventional SmO(2) was reduced to 42.6 +/- 6.1% and that of the cyclic SmO(2) to 48.5 +/- 5.6%. The reduction agrees with the general expectation. The cyclic SmO(2) is a promising new measure of muscle oxygenation.
本文提出了一种利用近红外光谱（NIRS）测量肌肉氧饱和度（SmO2）的新方法。该方法利用运动过程中经常被视为“运动伪影”的循环 NIRS 信号。这种新的测量方法，我们称之为“循环 SmO2”，与传统的 NIRS 技术相比，受肌红蛋白的影响可能较小，因为肌红蛋白通常与血红蛋白难以区分。与传统的 SmO2 相比，循环 SmO2 的假设也更少，后者使用时间、相位和空间分辨光谱方法进行测量。在一项循环运动研究中，对 11 名受试者的股外侧肌进行了 NIRS 测量。在轻度运动方案中，常规 SmO2 的组平均值为 51.7±4.3%，循环 SmO2 的组平均值为 56.0±3.9%。紧接着是一项剧烈运动方案，常规 SmO2 的组平均值降至 42.6±6.1%，循环 SmO2 的组平均值降至 48.5±5.6%。这种降低与一般预期相符。循环 SmO2 是一种很有前途的肌肉氧合新测量方法。
