Department of Sports Dentistry, Tokyo Dental College; Nihon University School of Medicine, Tokyo, Japan.
Adv Exp Med Biol. 2010;662:479-84. doi: 10.1007/978-1-4419-1241-1_69.
The purpose of this study was to elucidate the influence of bite force control on oxygenated hemoglobin (OxyHb) levels in regional cerebral blood flow as an indicator of brain activity in the premotor area. Healthy right-handed volunteers with no subjective or objective symptoms of problems of the stomatognathic system or cervicofacial region were included. Functional near-infrared spectroscopy (fNIRS) was used to determine OxyHb levels in the premotor area during bite force control. A bite block equipped with an occlusal force sensor was prepared to measure clenching at the position where the right upper and lower canine cusps come into contact. Intensity of clenching was shown on a display and feedback was provided to the subjects. Intensity was set at 20, 50 and 80% of maximum voluntary teeth clenching force. To minimize the effect of the temporal muscle on the working side of the jaw, the fNIRS probes were positioned contralaterally, in the left region. The findings of this study are: activation of the premotor area with bite force control was noted in all subjects, and in the group analysis OxyHb in the premotor cortex was significantly increased as the clenching strengthened at 20, 50 and 80% of maximum voluntary clenching force. These results suggest there is a possibility that the premotor area is involved in bite force control.
本研究旨在阐明在咀嚼力控制过程中，作为大脑活动指标的局部脑血流中氧合血红蛋白（OxyHb）水平的变化。纳入的健康右利手志愿者没有口颌系统或颈面部问题的主观或客观症状。功能性近红外光谱（fNIRS）用于测量咀嚼力控制过程中运动前区的 OxyHb 水平。准备了一个带有咬合力传感器的咬合块，以测量右上和下犬齿接触时的咬紧程度。显示屏上显示了咬紧的强度，并向受试者提供反馈。强度设置为最大自主咬牙力的 20%、50%和 80%。为了将颞肌对下颌工作侧的影响降到最低，fNIRS 探头放置在对侧的左侧区域。本研究的结果是：所有受试者在进行咀嚼力控制时都激活了运动前区，在组分析中，当咬紧程度在最大自主咬紧力的 20%、50%和 80%时，运动前皮质中的 OxyHb 明显增加。这些结果表明，运动前区可能参与了咀嚼力控制。
