Sasaguri Kenichi, Otsuka Takero, Tsunashima Hiroyuki, Shimazaki Tateshi, Kubo Kin-Ya, Onozuka Minoru
Division of Orthodontics, Department of Oral Science, Kanagawa Dental University Graduate School, 82 Inaoka-cho, 238-8580 Yokosuka, Kanagawa Japan.
Division of Brain functions and Neuroscience, Department of Oral Science, Kanagawa Dental University Graduate School, Yokosuka, Kanagawa Japan.
Int J Stomatol Occlusion Med. 2015;8(1):22-28. doi: 10.1007/s12548-015-0122-x. Epub 2015 Mar 27.
The aim of this study was to examine, after setting several restorations, the influence of adjusted occlusal interference during gum chewing on blood flow in the prefrontal area as determined using near-infrared spectroscopy.
The physiological rate was assessed using a visual analog scale (VAS) questionnaire. We selected 16 patients who desired prosthetic restorative treatment on the lateral dentition, and eight healthy volunteers. Subjects were divided into three eight-person groups. One group received restorations on the premolar area (PA), another group received restorations on the molar area (MA), and the control group (CT) received no prosthetic restorations. The spectroscope was fastened to the frontal region of the head after placement of the final restoration, but before adjustment.
Pre-adjustment (first gum chewing for CT) blood flow in the prefrontal cortex was measured during gum chewing. Blood flow was again measured during gum chewing after the restoration (second gum chewing for CT) had been adjusted in accordance with the subjective assessment of the patient while wearing the device. The VAS provided quantification of comfort during gum chewing before and after restoration adjustment. For the PA and MA groups, adjusting restorations decreased discomfort significantly during gum chewing. Moreover, in the MA group, prefrontal blood flow was significantly reduced, and blood flow correlated with discomfort.
Activation of the prefrontal area may provide an objective criterion for judging the functionality of occlusion after prosthetic occlusal reconstruction and/or orthodontics.
本研究的目的是在设置多个修复体后，使用近红外光谱法检测咀嚼口香糖期间调整的咬合干扰对前额叶区域血流的影响。
使用视觉模拟量表（VAS）问卷评估生理速率。我们选择了16名希望对侧牙列进行修复治疗的患者和8名健康志愿者。受试者分为三个八人组。一组在前磨牙区（PA）接受修复，另一组在磨牙区（MA）接受修复，对照组（CT）未接受修复。在最终修复体就位后但在调整之前，将光谱仪固定在头部的前额区域。
在咀嚼口香糖期间测量了调整前（CT组第一次咀嚼口香糖）前额叶皮质的血流。在根据患者佩戴装置时的主观评估调整修复体后（CT组第二次咀嚼口香糖），再次在咀嚼口香糖期间测量血流。VAS对修复体调整前后咀嚼口香糖期间的舒适度进行了量化。对于PA组和MA组，调整修复体显著降低了咀嚼口香糖期间的不适感。此外，在MA组中，前额叶血流显著减少，且血流与不适感相关。
前额叶区域的激活可能为判断修复性咬合重建和/或正畸治疗后咬合功能提供客观标准。
