Alonso Inmaculada, Hernández-Guerra Manuel, González Yanira, Gimeno-García Antonio, Méndez Rafael, Malagón Antonio, Quintero Carrión Enrique
Servicio de Aparato Digestivo, Hospital Universitario de Canarias, Tenerife, España.
Gastroenterol Hepatol. 2010 Apr;33(4):303-6. doi: 10.1016/j.gastrohep.2009.12.005. Epub 2010 Mar 4.
Solitary fibrous tumor (SFT) is a rare neoplasm of mesenchymal origin. The most commonly reported locations are the pleura and meninges. Less frequently, SFT manifests as an asymptomatic mass in the pancreas, liver, peritoneum or kidney. Clinical and radiological findings have failed to provide any specific diagnostic pattern but allow malignant development to be suspected due to infiltration or metastasis. In addition, preoperative cytology often yields inconclusive or misleading results. Therefore the definitive diagnosis is achieved after both surgical resection and immunohistochemical analysis, with markers such as CD34, vimentin and desmin. We present a case of SFT, which was difficult to diagnose, even after an extensive battery of tests based on imaging techniques.
孤立性纤维性肿瘤（SFT）是一种罕见的间叶源性肿瘤。最常报道的发病部位是胸膜和脑膜。较少见的情况是，SFT表现为胰腺、肝脏、腹膜或肾脏的无症状肿块。临床和影像学检查结果未能提供任何特异性诊断模式，但由于存在浸润或转移，可怀疑有恶性进展。此外，术前细胞学检查结果往往不明确或具有误导性。因此，通过手术切除及免疫组化分析，使用CD34、波形蛋白和结蛋白等标志物，才能做出明确诊断。我们报告一例SFT病例，即使在进行了一系列基于成像技术的广泛检查后，该病例仍难以诊断。
