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收缩带病变的临床与病理研究:与急性心肌梗死及不明原因猝死的关系

Clinical and pathologic studies on contraction band lesion: relation to acute myocardial infarction and unexplained sudden death.

作者信息

Teraoka K, Kaneko N, Takeishi M

机构信息

First Department of Pathology, Tokyo Women's Medical College, Japan.

出版信息

Mod Pathol. 1991 Jan;4(1):6-12.

PMID:2020661
Abstract

The relation between contraction band lesion (CBL) and major cause of death was investigated through the use of hearts from 500 serialized autopsy cases. Acute myocardial infarction (AMI), unexplained sudden death (USD), cardiac surgery death, cancer, infection, cerebrovascular disease, and ruptured aortic aneurysm were examined with respect to age, sex, heart weight, and CBL localization patterns. CBL was observed frequently with AMI, USD, and cardiac surgery death, but virtually unseen with cancer or in the remaining disease categories. In a comparison of average heart weight among the various groups, there appeared to be a correlation between heavy heart weight and increased frequency of CBL. In a second investigational phase, the relation between CBL and application of cardiopulmonary resuscitation techniques was investigated in 100 separate autopsy cases. There was no significant difference between treated and untreated patients regarding frequency and pathology of CBL. We hypothesize that CBL-AMI and CBL-USD belong to the same disease group and that CBL develops before the onset of death with no connection to the mechanical and pharmacologic effects of cardiopulmonary resuscitation.

摘要

通过对500例连续尸检病例的心脏进行研究,探讨了收缩带病变(CBL)与主要死因之间的关系。对急性心肌梗死(AMI)、不明原因猝死(USD)、心脏手术死亡、癌症、感染、脑血管疾病和主动脉瘤破裂进行了年龄、性别、心脏重量和CBL定位模式方面的检查。CBL在AMI、USD和心脏手术死亡中经常观察到,但在癌症或其他疾病类别中几乎未见。在比较不同组的平均心脏重量时,心脏重量较重与CBL频率增加之间似乎存在相关性。在第二个研究阶段,在100例单独的尸检病例中研究了CBL与心肺复苏技术应用之间的关系。在CBL的频率和病理方面,治疗组和未治疗组患者之间没有显著差异。我们假设CBL-AMI和CBL-USD属于同一疾病组,并且CBL在死亡发生之前就已出现,与心肺复苏的机械和药物作用无关。

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