Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, MetroHealth Medical Center, Case Western Reserve University, Cleveland, OH, USA.
Am J Obstet Gynecol. 2010 Mar;202(3):245.e1-245.e12. doi: 10.1016/j.ajog.2010.01.051.
We sought to determine maternal and neonatal outcomes by labor onset type and gestational age.
We used electronic medical records data from 10 US institutions in the Consortium on Safe Labor on 115,528 deliveries from 2002 through 2008. Deliveries were divided by labor onset type (spontaneous, elective induction, indicated induction, unlabored cesarean). Neonatal and maternal outcomes were calculated by labor onset type and gestational age.
Neonatal intensive care unit admissions and sepsis improved with each week of gestational age until 39 weeks (P < .001). After adjusting for complications, elective induction of labor was associated with a lower risk of ventilator use (odds ratio [OR], 0.38; 95% confidence interval [CI], 0.28-0.53), sepsis (OR, 0.36; 95% CI, 0.26-0.49), and neonatal intensive care unit admissions (OR, 0.52; 95% CI, 0.48-0.57) compared to spontaneous labor. The relative risk of hysterectomy at term was 3.21 (95% CI, 1.08-9.54) with elective induction, 1.16 (95% CI, 0.24-5.58) with indicated induction, and 6.57 (95% CI, 1.78-24.30) with cesarean without labor compared to spontaneous labor.
Some neonatal outcomes improved until 39 weeks. Babies born with elective induction are associated with better neonatal outcomes compared to spontaneous labor. Elective induction may be associated with an increased hysterectomy risk.
我们旨在通过临产类型和胎龄来确定母婴结局。
我们使用了来自 2002 年至 2008 年 10 家美国安全分娩联盟机构的电子病历数据,对 115528 例分娩进行了研究。分娩按照临产类型(自发临产、择期引产、有指征地引产、未临产剖宫产)进行分类。根据临产类型和胎龄计算新生儿和产妇结局。
新生儿重症监护病房(NICU)入院率和败血症随着胎龄的增加而提高,直至 39 周(P<.001)。在调整了并发症后,择期引产与呼吸机使用率(比值比[OR],0.38;95%置信区间[CI],0.28-0.53)、败血症(OR,0.36;95% CI,0.26-0.49)和 NICU 入院率(OR,0.52;95% CI,0.48-0.57)降低相关,与自发临产相比。择期引产在足月时行子宫切除术的相对风险为 3.21(95% CI,1.08-9.54),有指征地引产为 1.16(95% CI,0.24-5.58),而无临产剖宫产为 6.57(95% CI,1.78-24.30),与自发临产相比。
一些新生儿结局在 39 周前有所改善。与自发临产相比,择期引产分娩的婴儿有更好的新生儿结局。择期引产可能与子宫切除术风险增加有关。