发育中人胎盘的 AMP 脱氨酶。

AMP-deaminase from developing human placenta.

机构信息

Department of Biochemistry and Clinical Physiology, Medical University of Gdansk, Debinki 1, 80-211 Gdansk, Poland.

出版信息

Placenta. 2010 May;31(5):460-2. doi: 10.1016/j.placenta.2010.02.009. Epub 2010 Mar 6.

DOI:10.1016/j.placenta.2010.02.009

PMID:20207414

Abstract

During pregnancy the activity of AMP-deaminase in developing human placenta gradually decreases, being in homogenates of mature, term placenta (approximately 40 week of gestation) one fourth to one third of that in homogenates of immature (approximately 25 week of gestation) organ. The gradual decrease of activity correlates inversely with the increasing presence of the form of enzyme predominating in homogenates of the mature placenta. The discrepancy observed indicate that isozymic pattern of AMP-deaminase in developing human placenta changes.

摘要

在妊娠期间，人胎盘发育过程中 AMP 脱氨酶的活性逐渐降低，成熟（约 40 孕周）胎盘中匀浆的活性约为未成熟（约 25 孕周）胎盘中匀浆的活性的四分之一至三分之一。活性的逐渐降低与成熟胎盘匀浆中占优势的同工酶形式的出现呈负相关。观察到的差异表明，人胎盘发育过程中 AMP 脱氨酶的同工酶模式发生了变化。