Tuset Montse, López-Suñé Ester, Cervera Carlos, Moreno Asunción, Miró José M
Servicio de Farmacia, Institut d?Investigacions Biomèdiques August Pi i Sunyer, Hospital Clínic Universitari, Barcelona, España.
Enferm Infecc Microbiol Clin. 2010 Mar;28(3):199.e1-199.e33. doi: 10.1016/j.eimc.2009.11.002. Epub 2010 Mar 7.
This article aims to review herpes simplex, herpes zoster and cytomegalovirus and to summarize the main characteristics of the antiviral drugs available to treat those infections. The review of each drug focuses on dosage according to the treatment indication, dose adjustment in patients with impaired renal or hepatic function, the main pharmacokinetic features, and the most significant adverse effects and drug interactions.
本文旨在综述单纯疱疹、带状疱疹和巨细胞病毒,并总结可用于治疗这些感染的抗病毒药物的主要特点。对每种药物的综述重点在于根据治疗指征的剂量、肾功能或肝功能受损患者的剂量调整、主要药代动力学特征以及最显著的不良反应和药物相互作用。