Suppr超能文献

药物治疗差异:药物治疗中的种族、民族和性别差异。

Pharmacotherapeutic disparities: racial, ethnic, and sex variations in medication treatment.

机构信息

Health Disparities Initiatives and Community Outreach, College of Pharmacy, University of Arizona, Tucson, AZ, USA.

出版信息

Am J Health Syst Pharm. 2010 Mar 15;67(6):462-8. doi: 10.2146/ajhp090161.

Abstract

PURPOSE

Variations in the medication treatment received by racial and ethnic minorities and women and the negative health outcomes associated with these differences were examined.

METHODS

Studies published between January 1990 and June 2008 were identified via electronic searches of MEDLINE, PsychINFO, International Pharmaceutical Abstracts, PubMed, and CINAHL using search terms related to race, ethnicity, sex, drug treatment, and disparity or variation. Articles were excluded if they addressed only medical or surgical care or did not include a statistical analysis of differences in drug treatment based on race, ethnicity, or sex. Data regarding the frequency of reported race, ethnic, and sex differences in medication treatment, the types of treatment differences observed, and associated health outcomes were extracted.

RESULTS

A total of 311 research articles were identified that investigated whether race, ethnicity, or sex was associated with disparities in medication treatment. Seventy- seven percent (n = 240) of included articles revealed significant disparities in drug treatment across race, ethnicity, and sex (p < 0.05). The most frequent disparity, found in 73% of the articles studied, was differences in the receipt of prescription drugs; however, documented disparities occurred related to differences in the drugs prescribed, drug dosing or administration, and wait time to receipt of a drug. Documented outcomes associated with pharmacotherapeutic disparities included increased rates of hospitalization, decreased rates of therapeutic goal attainment (e.g., low- density-lipoprotein cholesterol, blood pressure goals), and decreased rates of survival.

CONCLUSION

A literature review revealed significant disparities in the medication treatment received by racial and ethnic minorities and women.

摘要

目的

研究了种族、民族和性别差异导致的药物治疗差异以及这些差异与不良健康后果之间的关系。

方法

通过电子搜索 MEDLINE、PsychINFO、国际药学文摘、PubMed 和 CINAHL,使用与种族、民族、性别、药物治疗以及差异或变化相关的搜索词,确定了 1990 年 1 月至 2008 年 6 月期间发表的研究。如果文章仅涉及医疗或手术护理,或者不包括基于种族、民族或性别的药物治疗差异的统计分析,则将其排除在外。提取有关药物治疗报告的种族、民族和性别差异的频率、观察到的治疗差异类型以及相关健康结果的数据。

结果

共确定了 311 篇研究文章,这些文章调查了种族、民族或性别是否与药物治疗差异相关。纳入的文章中有 77%(n=240)显示药物治疗在种族、民族和性别方面存在显著差异(p<0.05)。最常见的差异是 73%的文章中发现的处方药差异;然而,还记录了与处方药物、药物剂量或给药以及药物治疗等待时间相关的差异。与药物治疗差异相关的记录结果包括住院率增加、治疗目标达成率降低(例如,低密度脂蛋白胆固醇、血压目标)以及生存率降低。

结论

文献综述显示,少数民族和女性在药物治疗方面存在显著差异。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验