Parente Raphael Câmara Medeiros, de Freitas Vilmon, de Moura Neto Rodrigo Soares, de Oliveira Marco Aurélio Pinho, Lasmar Ricardo Bassil, Patriarca Marisa Teresinha, Canavez Felipe Simões
Ginecologista do Ministério da Saúde e da Universidade Federal do Rio de Janeiro - UFRJ - Rio de Janeiro (RJ), Brasil.
Rev Bras Ginecol Obstet. 2010 Jan;32(1):33-8. doi: 10.1590/s0100-72032010000100006.
to describe the clinical signs and symptoms of patients with bone metaplasia and to assess the risk factors for changes in these symptoms after removal of the bone fragment.
a cross-sectional study was conducted on 16 patients with a diagnosis of bone fragments in the uterine cavity during the period comprising July 2006 to January 2009. The inclusion criterion was the detection of a bone fragment removed from the uterine cavity. The presence of bone tissue in the endometrial cavity was histologically confirmed in all patients. The data of all patients were obtained before and after removal by means of a questionnaire for the evaluation of the effect of removal on the symptoms and for the search of possible factors related to the onset of the disease.
half the patients (8/16) had hemorrhagic symptoms and one third (6/16) were infertile. Removal of the fragments was quite effective in improving the complaints, with the disappearance of symptoms in all cases of hemorrhage and of pelvic pain.
removal of bone fragments can restore the fertility of selected patients whose infertility is caused by bone metaplasia and is quite effective in leading to improvement in patients with pelvic pain and menorrhage.
描述骨化生患者的临床体征和症状，并评估去除骨碎片后这些症状变化的危险因素。
对2006年7月至2009年1月期间诊断为宫腔内有骨碎片的16例患者进行了一项横断面研究。纳入标准是检测到从宫腔内取出的骨碎片。所有患者经组织学证实子宫内膜腔内存在骨组织。通过一份问卷获取所有患者在取出骨碎片前后的数据，该问卷用于评估取出对症状的影响以及寻找与疾病发病可能相关的因素。
一半患者（8/16）有出血症状，三分之一（6/16）不孕。取出碎片对改善症状相当有效，所有出血和盆腔疼痛病例的症状均消失。
去除骨碎片可恢复因骨化生导致不孕的部分患者的生育能力，并且对改善盆腔疼痛和月经过多的患者相当有效。
