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年龄会影响经皮肾镜取石术的治疗结果吗?

Does age affect outcomes of percutaneous nephrolithotomy?

作者信息

Karami Hossein, Mazloomfard Mohammad Mohsen, Golshan Alireza, Rahjoo Taban, Javanmard Babak

机构信息

Department of Urology, Shohada-e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Urol J. 2010 Winter;7(1):17-21.

Abstract

INTRODUCTION

The present study aimed to assess the efficacy and safety of percutaneous nephrolithotomy (PCNL) in elderly patients.

MATERIALS AND METHODS

We retrospectively reviewed 50 PCNLs performed in the elderly patients (age > 65 years) carried out in our clinic from 2001 through 2007 and compared those with 248 PCNLs performed in younger patients (age < 40 years) during the same period.

RESULTS

No significant difference was seen in calculus burden between the two groups. The success rates (stone-free patients and patients with residual calculi < 4 mm) were 85% for the elderly patients and 90% for the younger patients (P = .45). The major composition of calculi was calcium oxalate in 58% and 66.5% of the elderly and younger groups, respectively. No significant complication was observed in the elderly group. Fever without sign and symptoms of bacteremia was seen in 3 patients of each group (8.0% versus 1.2%, P = .004). The operative time was 75.0 +/- 6.4 minutes and 76.0 +/- 5.1 minutes (P = .25), and the mean hospital stay was 3.7 +/- 0.3 days and 3.8 +/- 0.9 days (P = .80) in the elderly and younger patients, respectively.

CONCLUSION

We found that PCNL in patients over 65 years was a safe and reliable technique with a stone-free rate of 85% for all types of calculi. Well-controlled comorbidities do not increase the risk of operation. It seems that despite the higher medical risk in the elderly patients, PCNL could be safe and yields a high stone-free rate.

摘要

引言

本研究旨在评估经皮肾镜取石术(PCNL)在老年患者中的疗效和安全性。

材料与方法

我们回顾性分析了2001年至2007年在我院为老年患者(年龄>65岁)实施的50例PCNL,并与同期为年轻患者(年龄<40岁)实施的248例PCNL进行比较。

结果

两组结石负荷无显著差异。老年患者的成功率(结石清除患者及残余结石<4mm的患者)为85%,年轻患者为90%(P = 0.45)。老年组和年轻组结石的主要成分分别为草酸钙,占58%和66.5%。老年组未观察到显著并发症。每组各有3例患者出现无菌血症体征和症状的发热(8.0%对1.2%,P = 0.004)。老年患者和年轻患者的手术时间分别为75.0±6.4分钟和76.0±5.1分钟(P = 0.25),平均住院时间分别为3.7±0.3天和3.8±0.9天(P = 0.80)。

结论

我们发现,65岁以上患者的PCNL是一种安全可靠的技术,对所有类型结石的结石清除率为85%。控制良好的合并症不会增加手术风险。尽管老年患者医疗风险较高,但PCNL似乎是安全的,且结石清除率较高。

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