Karami Hossein, Mazloomfard Mohammad Mohsen, Golshan Alireza, Rahjoo Taban, Javanmard Babak
Department of Urology, Shohada-e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Urol J. 2010 Winter;7(1):17-21.
The present study aimed to assess the efficacy and safety of percutaneous nephrolithotomy (PCNL) in elderly patients.
We retrospectively reviewed 50 PCNLs performed in the elderly patients (age > 65 years) carried out in our clinic from 2001 through 2007 and compared those with 248 PCNLs performed in younger patients (age < 40 years) during the same period.
No significant difference was seen in calculus burden between the two groups. The success rates (stone-free patients and patients with residual calculi < 4 mm) were 85% for the elderly patients and 90% for the younger patients (P = .45). The major composition of calculi was calcium oxalate in 58% and 66.5% of the elderly and younger groups, respectively. No significant complication was observed in the elderly group. Fever without sign and symptoms of bacteremia was seen in 3 patients of each group (8.0% versus 1.2%, P = .004). The operative time was 75.0 +/- 6.4 minutes and 76.0 +/- 5.1 minutes (P = .25), and the mean hospital stay was 3.7 +/- 0.3 days and 3.8 +/- 0.9 days (P = .80) in the elderly and younger patients, respectively.
We found that PCNL in patients over 65 years was a safe and reliable technique with a stone-free rate of 85% for all types of calculi. Well-controlled comorbidities do not increase the risk of operation. It seems that despite the higher medical risk in the elderly patients, PCNL could be safe and yields a high stone-free rate.
本研究旨在评估经皮肾镜取石术(PCNL)在老年患者中的疗效和安全性。
我们回顾性分析了2001年至2007年在我院为老年患者(年龄>65岁)实施的50例PCNL,并与同期为年轻患者(年龄<40岁)实施的248例PCNL进行比较。
两组结石负荷无显著差异。老年患者的成功率(结石清除患者及残余结石<4mm的患者)为85%,年轻患者为90%(P = 0.45)。老年组和年轻组结石的主要成分分别为草酸钙,占58%和66.5%。老年组未观察到显著并发症。每组各有3例患者出现无菌血症体征和症状的发热(8.0%对1.2%,P = 0.004)。老年患者和年轻患者的手术时间分别为75.0±6.4分钟和76.0±5.1分钟(P = 0.25),平均住院时间分别为3.7±0.3天和3.8±0.9天(P = 0.80)。
我们发现,65岁以上患者的PCNL是一种安全可靠的技术,对所有类型结石的结石清除率为85%。控制良好的合并症不会增加手术风险。尽管老年患者医疗风险较高,但PCNL似乎是安全的,且结石清除率较高。