Chandir Subhash, Hussain Hamidah, Salahuddin Naseem, Amir Mohammad, Ali Farheen, Lotia Ismat, Khan Amir Javed
Interactive Research & Development, Karachi, Pakistan.
J Pak Med Assoc. 2010 Feb;60(2):105-9.
To describe the types and treatment outcomes of the extra-pulmonary tuberculosis (EPTB) cases in a tertiary care hospital in a high burden tuberculosis country.
A retrospective case series study was conducted at Liaquat National Hospital (LNH), the largest private tertiary care hospital in Karachi, Pakistan. All cases diagnosed and treated as EPTB between November 2005 and February 2007 were included. Data was retrieved from medical records on demographics, clinical, laboratory, and outcome status.
A total of 194 patients treated for EPTB were identified. Mean age of patients was 34 +/- 16.4 years, and 75% of patients were female. Lymph nodes and spine were the most common sites involved (60%). The cure rate was 40.7%. There was no difference in cure rate of males and females (p=0.99).
EPTB is an important clinical problem in Pakistan. Due to lack of guidelines for diagnosis and duration of treatment in EPTB most physicians in Pakistan treat patients based on clinical symptoms and for prolonged duration of 12, to even as long as 24 months. The National TB Program, and chest and infectious disease societies must develop standardized guidelines for the diagnosis and treatment of EPTB.
描述在一个结核病高负担国家的三级医疗医院中肺外结核病（EPTB）病例的类型及治疗结果。
在巴基斯坦卡拉奇最大的私立三级医疗医院利亚卡特国家医院（LNH）开展一项回顾性病例系列研究。纳入2005年11月至2007年2月期间所有诊断并治疗为EPTB的病例。从病历中获取有关人口统计学、临床、实验室及结局状况的数据。
共确定了194例接受EPTB治疗的患者。患者的平均年龄为34±16.4岁，75%的患者为女性。淋巴结和脊柱是最常受累的部位（60%）。治愈率为40.7%。男性和女性的治愈率无差异（p = 0.99）。
EPTB在巴基斯坦是一个重要的临床问题。由于缺乏EPTB的诊断和治疗疗程指南，巴基斯坦的大多数医生根据临床症状治疗患者，治疗时间长达12个月，甚至长达24个月。国家结核病规划以及胸部和传染病学会必须制定EPTB诊断和治疗的标准化指南。
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