Hossain Nazli, Farzana Tasneem, Khan Nusrat Hasan, Shamsi Tahir Sultan, James Andra H
Department of Obstetrics & Gynecology Unit-3, Dow University of Health Sciences & Civil Hospital Karachi.
J Pak Med Assoc. 2010 Feb;60(2):127-9.
The prevalence of menorrhagia in adolescent populations with bleeding disorders varies between 14% to 48%. The common conditions associated with menorrhagia include von Willebrand disease (VWD), platelet function disorders and coagulation factor deficiencies. The majority of studies, which have been conducted in the West, report VWD, as the most common inherited bleeding disorder leading to menorrhagia, whereas studies from South-East Asia have found platelet function disorder as the leading inherited bleeding disorder in women with menorrhagia. The other common conditions which can lead to increased blood loss in this age group are anovulatory bleeding and hormonal disorders. We report here three cases of adolescent menorrhagia due to platelet function disorders, along with review of literature.
患有出血性疾病的青少年人群中月经过多的患病率在14%至48%之间。与月经过多相关的常见病症包括血管性血友病（VWD）、血小板功能障碍和凝血因子缺乏。大多数在西方进行的研究报告称，血管性血友病是导致月经过多的最常见遗传性出血性疾病，而东南亚的研究发现血小板功能障碍是月经过多女性中主要的遗传性出血性疾病。在这个年龄组中，其他可导致失血增加的常见病症是无排卵性出血和激素紊乱。我们在此报告三例因血小板功能障碍导致的青少年月经过多病例，并对文献进行综述。
