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[白塞病的静脉受累:28例病例系列]

[Venous involvement in Behcet's disease: a series of 28 cases].

作者信息

Jamoussi Sonia Ketari, Chaaba Hatem, Ben Dhaou Besma, Kochbati Samir, Boussema Fatma, Cherif Ouahida, Rokbani Lilia

机构信息

Service de médecine interne, hôpital Habib Thameur, Tunis Tunisie.

出版信息

Tunis Med. 2009 Dec;87(12):829-33.

PMID:20209850
Abstract

BACKGROUND

Venous involvement is a rare and severe clinical feature in Behcet disease (BD).

AIM

We reported our experience with a rare and interesting subset of BD patients with venous involvement.

METHODS

From 1994 to 2008, twenty eight cases of venous BD were found amongst BD patients in the department of internal medicine of Habib Thameur Hospital.

RESULTS

45 episodes of venous thrombosis occurred in 28 patients. There were 25 men and 3 women the mean age when venous involvement manifested was diagnosed was about 32.25. Venous thrombosis occur in the first five years following the diagnosis of BD. Pericarditis was more frequently noted in patients with venous BD than others without vasculo-Behcet disease. In contrast digestive and rheumatologic symptoms were more likely observed in patients without vasculo-Behcet disease. Thirteen patients underwent corticosteroids. Relapses occurred more frequently in patients without corticosteroid therapy.

CONCLUSION

Venous involvement is more frequently noted in vasculo-Behcet than arterial involvement. Its treatment should include anticoagulation in association with corticosteroids.

摘要

背景

静脉受累是白塞病(BD)中一种罕见且严重的临床特征。

目的

我们报告了对白塞病合并静脉受累这一罕见且有趣的患者亚组的治疗经验。

方法

1994年至2008年期间,在哈比卜·塔穆尔医院内科的白塞病患者中发现了28例静脉型白塞病患者。

结果

28例患者共发生45次静脉血栓形成。其中男性25例,女性3例,静脉受累表现被诊断时的平均年龄约为32.25岁。静脉血栓形成发生在白塞病诊断后的前五年。与无血管型白塞病的患者相比,静脉型白塞病患者更常出现心包炎。相比之下,无血管型白塞病的患者更易出现消化系统和风湿性症状。13例患者接受了皮质类固醇治疗。未接受皮质类固醇治疗的患者复发更频繁。

结论

血管型白塞病中静脉受累比动脉受累更常见。其治疗应包括抗凝治疗并联合使用皮质类固醇。

相似文献

1
[Venous involvement in Behcet's disease: a series of 28 cases].[白塞病的静脉受累:28例病例系列]
Tunis Med. 2009 Dec;87(12):829-33.
2
[Arterial involvement in Behcet's disease: a series of 7 cases].[白塞病的动脉受累:7例病例系列]
Tunis Med. 2009 Sep;87(9):583-8.
3
Vascular involvement in Behçet's disease: a retrospective analysis of 2319 cases.白塞病的血管受累情况:2319例病例的回顾性分析
Int J Dermatol. 2006 Aug;45(8):919-21. doi: 10.1111/j.1365-4632.2006.02832.x.
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Major arterial involvement and review of Behcet's disease.大动脉受累与白塞病综述
Ann Vasc Surg. 2007 Mar;21(2):232-9. doi: 10.1016/j.avsg.2006.12.004.
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Behcet disease in adult Druzes in north Israel: the influence of ethnic origin on disease expression and severity.以色列北部成年德鲁兹人中的白塞病:种族起源对疾病表现和严重程度的影响。
J Clin Rheumatol. 2007 Jun;13(3):124-7. doi: 10.1097/RHU.0b013e3180645878.
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Cerebral venous thrombosis in Behçet's disease.白塞病中的脑静脉血栓形成
Arthritis Rheum. 2009 Apr 15;61(4):518-26. doi: 10.1002/art.24393.
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Effects of factor V gene G1691A, methylenetetrahydrofolate reductase gene C677T, and prothombin gene G20210A mutations on deep venous thrombogenesis in Behçet's disease.因子V基因G1691A、亚甲基四氢叶酸还原酶基因C677T和凝血酶原基因G20210A突变对白塞病深静脉血栓形成的影响。
J Rheumatol. 2000 Dec;27(12):2849-54.
8
[Vascular symptoms of Behcet's disease].[白塞病的血管症状]
Ter Arkh. 2005;77(5):39-41.
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The presentation of headache in neuro-Behçet's disease: a case-series.神经白塞病中头痛的表现:病例系列
Headache. 2009 Mar;49(3):467-70. doi: 10.1111/j.1526-4610.2008.01265.x.
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Characteristics of vascular involvement in Behçet's disease.白塞病血管受累的特征。
Scand J Rheumatol. 2006 Jan-Feb;35(1):65-8. doi: 10.1080/03009740500255761.

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