Imperial College, St. Stephens AIDS Trust, Chelsea and Westminster Hospital, London, UK.
Antiviral Res. 2010 May;86(2):224-6. doi: 10.1016/j.antiviral.2010.02.324. Epub 2010 Mar 6.
Therapy for infection with HIV-2 remains limited. We report an HIV-2-infected patient in whom genotyping demonstrated PI, NRTI and NNRTI resistance, with a subsequent response to raltegravir- and maraviroc-based therapy. Further studies are required to assess the clinical efficacy of maraviroc in HIV-2 infection.
治疗 HIV-2 感染的方法仍然有限。我们报告了一例 HIV-2 感染患者,基因分型显示存在对 PI、NRTI 和 NNRTI 的耐药性,随后对基于 raltegravir 和 maraviroc 的治疗有反应。需要进一步研究来评估 maraviroc 在 HIV-2 感染中的临床疗效。