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M-3 清单的可行性和诊断有效性:一种简短的、自我评估的抑郁、双相情感障碍、焦虑和创伤后应激障碍在初级保健中的筛查工具。

Feasibility and diagnostic validity of the M-3 checklist: a brief, self-rated screen for depressive, bipolar, anxiety, and post-traumatic stress disorders in primary care.

机构信息

Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599-7160, USA.

出版信息

Ann Fam Med. 2010 Mar-Apr;8(2):160-9. doi: 10.1370/afm.1092.

Abstract

PURPOSE

Mood and anxiety disorders are the most common psychiatric conditions seen in primary care, yet they remain underdetected and undertreated. Screening tools can improve detection, but available instruments are limited by the number of disorders assessed. We wanted to assess the feasibility and diagnostic validity of the My Mood Monitor (M-3) checklist, a new, 1-page, patient-rated, 27-item tool developed to screen for multiple psychiatric disorders in primary care.

METHODS

We enrolled a sample of 647 consecutive participants aged 18 years and older who were seeking primary care at an academic family medicine clinic between July 2007 and February 2008. We used a 2-step scoring procedure to make screening more efficient. The main outcomes measured were the sensitivity and specificity of the M-3 for major depression, bipolar disorder, any anxiety disorder, and post-traumatic stress disorder (PTSD), a specific type of anxiety disorder. Using a split sample technique, analysis proceeded from determination of optimal screening thresholds to assessment of the psychometric properties of the self-report instrument using the determined thresholds. We used the Mini International Neuropsychiatric Interview as the diagnostic standard. Feasibility was assessed with patient and physician exit questionnaires.

RESULTS

The depression module had a sensitivity of 0.84 and a specificity of 0.80. The bipolar module had a sensitivity of 0.88, and a specificity of 0.70. The anxiety module had a sensitivity of 0.82 and a specificity of 0.78, and the PTSD module had a sensitivity of 0.88 and a specificity of 0.76. As a screen for any psychiatric disorder, sensitivity was 0.83 and specificity was 0.76. Patients took less than 5 minutes to complete the M-3 in the waiting room, and less than 1% reported not having time to complete it. Eighty-three percent of clinicians reviewed the checklist in 30 or fewer seconds, and 80% thought it was helpful in reviewing patients' emotional health.

CONCLUSIONS

The M-3 demonstrates utility as a valid, efficient, and feasible tool for screening multiple common psychiatric illnesses, including bipolar disorder and PTSD, in primary care. Its diagnostic accuracy equals that of currently used single-disorder screens and has the additional benefit of being combined into a 1-page tool. The M-3 potentially can reduce missed psychiatric diagnoses and facilitate proper treatment of identified cases.

摘要

目的

情绪和焦虑障碍是初级保健中最常见的精神疾病,但它们的检出率和治疗率仍然较低。筛查工具可以提高检出率,但现有的工具受到评估障碍数量的限制。我们想评估 My Mood Monitor(M-3)检查表的可行性和诊断有效性,这是一种新的、1 页、患者自评、27 项的工具,用于在初级保健中筛查多种精神疾病。

方法

我们招募了 2007 年 7 月至 2008 年 2 月期间在学术家庭医学诊所寻求初级保健的 647 名连续患者,年龄在 18 岁及以上。我们使用了两步评分程序来提高筛查效率。主要结果是 M-3 对重性抑郁障碍、双相障碍、任何焦虑障碍和创伤后应激障碍(PTSD)的敏感性和特异性,PTSD 是一种特殊类型的焦虑障碍。使用分样技术,从确定最佳筛查阈值开始分析,然后使用确定的阈值评估自我报告工具的心理测量特性。我们使用 Mini International Neuropsychiatric Interview 作为诊断标准。使用患者和医生退出问卷评估可行性。

结果

抑郁模块的敏感性为 0.84,特异性为 0.80。双相模块的敏感性为 0.88,特异性为 0.70。焦虑模块的敏感性为 0.82,特异性为 0.78,PTSD 模块的敏感性为 0.88,特异性为 0.76。作为任何精神疾病的筛查,敏感性为 0.83,特异性为 0.76。患者在候诊室不到 5 分钟即可完成 M-3,不到 1%的患者报告没有时间完成。83%的临床医生在 30 秒或更短的时间内审查清单,80%的人认为它有助于审查患者的情绪健康。

结论

M-3 证明是一种有效的、高效的、可行的工具,可用于在初级保健中筛查多种常见的精神疾病,包括双相障碍和 PTSD。其诊断准确性与目前使用的单一疾病筛查相同,并且具有将多种疾病合并到一个 1 页工具的额外优势。M-3 有可能减少遗漏的精神诊断,并促进对已识别病例的适当治疗。

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