Department of Otolaryngology, Taichung Veterans General Hospital, Taichung, Taiwan.
Eur J Clin Microbiol Infect Dis. 2010 May;29(5):551-4. doi: 10.1007/s10096-010-0894-2. Epub 2010 Mar 6.
This study was conducted to determine whether electrolysed acid water (EAW) increased the antibacterial effect of irrigating solution used in the management of chronic rhinosinusitis (CRS). One hundred CRS patients were recruited from April 2008 to February 2009. Four swab specimens were taken from the ipsilateral middle meatus of each patient and one was placed in a Thanswab tube, while the other three were each placed randomly in one of three glass tubes containing either 5 ml of EAW, distilled water or 70% alcohol. They were immediately sent to the laboratory for aerobic and anaerobic cultures. Bacteria grew from 36 specimens when they were placed in a Thanswab tube, from four when placed in a tube with EAW, 30 when placed in distilled water and two when placed in alcohol. The culture rate was significantly lower when the specimens were placed in a tube with EAW as compared with distilled water or in a Thanswab tube, but was not different compared with alcohol. The bacteria that grew from four specimens after first being processed by EAW were all anaerobes. This study showed that EAW exhibited an increased antibacterial effect on bacteria grown from the nasal discharge of CRS patients.
本研究旨在确定酸化水（EAW）是否能增强用于慢性鼻-鼻窦炎（CRS）管理的冲洗液的抗菌效果。2008 年 4 月至 2009 年 2 月，共招募了 100 名 CRS 患者。从每位患者的同侧中鼻道采集 4 个拭子标本，一个放入 Thanswab 管，另外 3 个随机放入 3 个玻璃管中，每个管中分别装有 5ml 的 EAW、蒸馏水或 70%酒精。立即将它们送到实验室进行需氧和厌氧培养。当将标本放入 Thanswab 管时，有 36 个标本生长出细菌，放入 EAW 管时，有 4 个标本生长出细菌，放入蒸馏水时，有 30 个标本生长出细菌，放入酒精时，有 2 个标本生长出细菌。与蒸馏水或 Thanswab 管相比，将标本放入 EAW 管时的培养率显著降低，但与酒精相比无差异。经过 EAW 处理的 4 个标本中生长出的所有细菌均为厌氧菌。本研究表明，酸化水对 CRS 患者鼻分泌物中生长的细菌具有增强的抗菌作用。
