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瑞士摇晃婴儿综合征:一项前瞻性随访研究的结果,2002-2007 年。

Shaken baby syndrome in Switzerland: results of a prospective follow-up study, 2002-2007.

机构信息

Child Protection Group, University Children's Hospital Zurich, Steinwiesstrasse 75, 8032, Zurich, Switzerland.

出版信息

Eur J Pediatr. 2010 Aug;169(8):1023-8. doi: 10.1007/s00431-010-1175-x. Epub 2010 Mar 7.

Abstract

Since the incidence of shaken baby syndrome in Switzerland was not known, we conducted a nationwide prospective follow-up study for a 5-year period (from 2002 to 2007). The data were collected through the Swiss Pediatric Surveillance Unit. Inclusion criteria were the presence, in a child <or=6 years of age, of 1) more than or equal to two clinical symptoms (altered consciousness, convulsions, respiratory irregularities, and bulging fontanel), 2) one eye finding (retinal hemorrhages, vitreous hemorrhages), 3) one MRI/CT finding (subdural hematoma, subarachnoid hematoma, and parenchymatous lesions), or 4) history of shaking. Exclusion criteria were age >6 years or documented accident/disease explaining symptoms/findings. To describe outcome, we used the King's Outcome Scale for Childhood Head Injury (KOSCHI). 56 cases were reported from 13 of 26 Swiss cantons, representing 80% of the Swiss population; 49 cases met the inclusion criteria. Preponderance of male infants was high (31 male and 18 female); median age at admission was 4 months (1-58). Clinical symptoms were present in 42 infants, retinal/vitreous hemorrhages in 39 infants, and pathological brain/head imaging in 46 infants. In 13 cases, the caregivers admitted shaking the child. Outcomes (KOSCHI 1-5; n = 47 patients) were death (KOSCHI 1) 8 (17.7%), vegetative state (KOSCHI 2) 0, severe disability (KOSCHI 3) 11 (22.2%), moderate disability (KOSCHI 4) 14 (31.1%), and good recovery (KOSCHI 5) 14 (28.8%). Based on these data, the incidence of shaken baby syndrome in Switzerland is 14 per 100 000 live births, which corresponds to the incidence in other Western countries. Demographic characteristics and outcomes of Swiss patients were comparable to published studies.

摘要

由于瑞士摇晃婴儿综合征的发病率尚不清楚,我们进行了一项为期 5 年的全国前瞻性随访研究(2002 年至 2007 年)。数据通过瑞士儿科监测单位收集。纳入标准为:1)6 岁以下儿童存在 2 种以上临床症状(意识改变、抽搐、呼吸不规则和前囟隆起),2)1 种眼部表现(视网膜出血、玻璃体积血),3)1 种 MRI/CT 发现(硬膜下血肿、蛛网膜下腔出血和实质病变),或 4)有摇晃史。排除标准为年龄大于 6 岁或有记录的意外/疾病可解释症状/发现。为了描述结局,我们使用了儿童头部损伤的 King 结局量表(KOSCHI)。从瑞士 26 个州中的 13 个州报告了 56 例病例,占瑞士人口的 80%;49 例符合纳入标准。男婴比例较高(31 例男性和 18 例女性);中位入院年龄为 4 个月(1-58 岁)。42 例婴儿存在临床症状,39 例婴儿存在视网膜/玻璃体积血,46 例婴儿存在病理性脑/头部影像学改变。13 例照顾者承认摇晃了婴儿。结局(KOSCHI 1-5;n = 47 例患者)为死亡(KOSCHI 1)8 例(17.7%),植物状态(KOSCHI 2)0 例,重度残疾(KOSCHI 3)11 例(22.2%),中度残疾(KOSCHI 4)14 例(31.1%),和良好恢复(KOSCHI 5)14 例(28.8%)。根据这些数据,瑞士摇晃婴儿综合征的发病率为每 10 万活产儿 14 例,与其他西方国家的发病率相当。瑞士患者的人口统计学特征和结局与已发表的研究相似。

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