Department of Otolaryngology, George Washington University, 2150 Pennsylvania Ave., NW, Suite 6-301, Washington, DC 20037, USA.
Laryngoscope. 2010 May;120(5):978-80. doi: 10.1002/lary.20876.
The authors describe a 38-year-old man who presented with hypernasality, perioral and acroparesthesia, dyspnea, and dysphagia. Further evaluation revealed a diagnosis of Miller-Fisher syndrome (MFS). MFS is a variant of Guillain-Barré syndrome previously described in neurology and critical care journals; however, there is a paucity of work concerning this disease in the otolaryngology literature. An acute change in voice usually occurs secondary to inflammatory processes as seen after intubation and infection, but can occur as part of a more complex disease entity such as Guillain-Barré or Miller-Fisher syndrome. As such, clinicians should consider this in their evaluation of rhinolalia aperta.
作者描述了一位 38 岁男性患者，其主要表现为鼻音过高、口周和肢端感觉异常、呼吸困难和吞咽困难。进一步检查诊断为 Miller-Fisher 综合征（MFS）。MFS 是吉兰-巴雷综合征的一种变异型，先前在神经病学和重症监护期刊中有过描述；然而，耳鼻喉科文献中关于这种疾病的研究很少。急性声音改变通常继发于炎症过程，如插管和感染后，但也可能是更复杂疾病实体的一部分，如吉兰-巴雷或 Miller-Fisher 综合征。因此，临床医生在评估开放性鼻音时应考虑到这一点。
