Shvarts P G, Kadykov A S, Shvedkov V V, Timerbaeva S L, Polevaia E V, Mulach A N
Urologiia. 2009 Sep-Oct(5):24-9.
Overactive bladder (OAB) is observed in such brain diseases as stroke, hypoxic ischemic encephalopathy, Parkinson's disease (PD), multiple sclerosis (MS). Trospium chloride (spasmex) was used in OAB patients with MS (n = 87), stroke (n = 83), encephalopathy (n = 47) and PD (n = 36) in doses from 15 to 45 mg/day in 2 to 36 month courses. The response with minimal side effects was achieved in 94% patients. In addition to basic effects, trospium chloride relieved spastic constipation in patients with stroke, hypersalivation in PD and anal incontinence in MS.
膀胱过度活动症（OAB）见于多种脑部疾病，如中风、缺氧缺血性脑病、帕金森病（PD）、多发性硬化症（MS）。氯化托烷司琼（斯帕沙星）用于患有MS（n = 87）、中风（n = 83）、脑病（n = 47）和PD（n = 36）的OAB患者，剂量为15至45毫克/天，疗程为2至36个月。94%的患者取得了副作用最小的疗效。除了基本疗效外，氯化托烷司琼还缓解了中风患者的痉挛性便秘、PD患者的唾液分泌过多以及MS患者的肛门失禁。
