Doerig C, Antonino A, Pache I, Moradpour D
Service de gastro-entérologie et d'hépatologie, CHUV, 1011 Lausanne.
Rev Med Suisse. 2010 Jan 27;6(233):168-70, 172-3.
Chronic hepatitis B predisposes to the development of cirrhosis and hepatocellular carcinoma. Treatment of chronic hepatitis B is aimed at halting viral replication and, thereby, hepatic inflammation. Treatment indication should be established carefully and with full knowledge of the advantages and limitations of currently available antiviral drugs. Patients on long-term nudcleos(t)ide analogue treatment should be followed regularly in order to avoid the appearance of antiviral resistance. The purpose of this review is to provide a concise overview of the diagnosis and management of chronic hepatitis B.
慢性乙型肝炎易发展为肝硬化和肝细胞癌。慢性乙型肝炎的治疗旨在阻止病毒复制,从而减轻肝脏炎症。应谨慎确定治疗指征,并充分了解现有抗病毒药物的优缺点。接受长期核苷(酸)类似物治疗的患者应定期随访,以避免出现抗病毒耐药性。本综述的目的是简要概述慢性乙型肝炎的诊断和管理。