Infectious Diseases Society of America, Arlington, Virginia 22209, USA.
Clin Infect Dis. 2010 Apr 15;50(8):1081-3. doi: 10.1086/652237.
The time has come for a global commitment to develop new antibacterial drugs. Current data document the impending disaster due to the confluence of decreasing investment in antibacterial drug research and development concomitant with the documented rapid increase in the level of resistance to currently licensed drugs. Despite the good faith efforts of many individuals, professional societies, and governmental agencies, the looming crisis has only worsened over the past decade.
现在是全球承诺开发新的抗菌药物的时候了。目前的数据记录了由于对抗菌药物研发投资减少,以及现有许可药物的耐药性迅速增加这两个因素的共同作用,即将面临的灾难。尽管许多个人、专业协会和政府机构都真诚地努力,但在过去十年中,这场迫在眉睫的危机只会恶化。