Department of Otolaryngology-Head & Neck Surgery, Mayo Clinic, Jacksonville, FL, USA.
Expert Rev Anticancer Ther. 2010 Mar;10(3):331-8. doi: 10.1586/era.10.10.
The decision to treat patients suffering from glottic cancer with either radiotherapy or surgery is both complex and controversial. Transoral laser microsurgery is a surgical technique that offers an attractive alternative therapy for laryngeal cancer. In addition to excellent oncologic outcomes and organ preservation, the benefits of transoral laser microsurgery include low morbidity and mortality, shorter periods of hospitalization and exceptional functional results. As the evidence base for the effectiveness of laser surgery grows, transoral laser microsurgery has become established as a valid surgical option for the treatment of early laryngeal cancer. In this article we examine the surgical technique and discuss the oncologic and functional outcomes of transoral laser microsurgery. Furthermore, we offer a vision of the future of endoscopic laser surgery for the management of cancer of the larynx and the upper aerodigestive tract.
治疗声门型癌症患者采用放疗还是手术的决策既复杂又存在争议。经口激光微创手术是一种为喉癌提供的极具吸引力的替代疗法。经口激光微创手术除了具有出色的肿瘤学效果和器官保留外,还具有低发病率和死亡率、较短的住院时间和极佳的功能结果等优点。随着激光手术有效性证据的增加,经口激光微创手术已成为治疗早期喉癌的有效手术选择。在本文中,我们检查了手术技术,并讨论了经口激光微创手术的肿瘤学和功能结果。此外,我们对内镜激光手术在管理喉和上呼吸道癌症方面的未来进行了展望。