Department of Biology, National Science Division, Pepperdine University, 24255 Pacific Coast Highway, Malibu, California 90263-4321, USA.
BMC Biol. 2010 Mar 9;8:20. doi: 10.1186/1741-7007-8-20.
The increased battery of molecular markers, derived from comparative genomics, is aiding our understanding of the genetics of domestication. The recent BMC Biology article pertaining to the evolution of small size in dogs is an example of how such methods can be used to study the origin and diversification of the domestic dog. We are still challenged, however, to appreciate the genetic mechanisms responsible for the phenotypic diversity seen in 'our best friend'.
越来越多的源自比较基因组学的分子标记正在帮助我们理解驯化的遗传学。最近发表在 BMC 生物学杂志上的一篇关于狗体型进化的文章,就是如何利用这些方法来研究家犬起源和多样化的一个例子。然而,我们仍然难以理解导致“我们最好的朋友”表现出的表型多样性的遗传机制。