Vullo Carlos, Borosky Alicia, Romanini Carola, Catelli Laura, Yamamoto Toshimichi
LIDMO, Independencia 644- 4to A, 5000 Córdoba, Argentina.
Forensic Sci Int Genet. 2010 Apr;4(3):e79-81. doi: 10.1016/j.fsigen.2009.06.006. Epub 2009 Jul 8.
Allele frequencies and forensic parameters for twelve miniSTR autosomal loci (D10S1248, D14S1434, D22S1045, D4S2364, D2S441, D1S1677, D20S480, D6S2439, D6S1056, D9S1118, D4S2639 and D17S1290) were calculated from a sample of 506 unrelated individuals from the Central-East Region of Argentina. No significant deviations from Hardy-Weinberg expectations were found. Furthermore, comparisons with other previously studied populations were made. These twelve miniSTR markers may help forensic laboratories in solving parentage testing as well as in typing degraded DNA samples.
从阿根廷中东部地区的506名无亲缘关系个体的样本中计算出12个常染色体微型短串联重复序列(miniSTR)基因座(D10S1248、D14S1434、D22S1045、D4S2364、D2S441、D1S1677、D20S480、D6S2439、D6S1056、D9S1118、D4S2639和D17S1290)的等位基因频率和法医学参数。未发现与哈迪-温伯格预期有显著偏差。此外,还与其他先前研究的人群进行了比较。这12个微型短串联重复序列标记可能有助于法医实验室解决亲子鉴定问题以及对降解的DNA样本进行分型。