Neuwirth Christoph, Mojon Daniel, Weber Markus
Neuromuscular Diseases Unit, Kantonsspital St. Gallen, St. Gallen, Switzerland.
J Clin Neuromuscul Dis. 2010 Mar;11(3):114-9. doi: 10.1097/CND.0b013e3181cc21de.
A patient with acute purely motor polyneuropathy with positive GD1a ganglioside antibodies who presented with paresis in combination with hyperreflexia is reported. Neurophysiological tests revealed features compatible with acute motor axonal neuropathy. Therapy with intravenous immunoglobulin led to rapid clinical improvement. However, at the time when signs of active denervation appeared on electromyographic testing, the patient developed bilateral papillitis. The pathogenesis of pure motor Guillain-Barré syndrome with hyperreflexia and papillitis is discussed.
报告了1例患有急性纯运动性多发性神经病且GD1a神经节苷脂抗体呈阳性的患者，该患者表现为轻瘫并伴有反射亢进。神经生理学检查显示符合急性运动轴索性神经病的特征。静脉注射免疫球蛋白治疗使临床症状迅速改善。然而，在肌电图检查出现失神经活动迹象时，该患者发生了双侧视乳头炎。本文讨论了伴有反射亢进和视乳头炎的纯运动性吉兰-巴雷综合征的发病机制。
