伊匹单抗治疗原发无治疗黑色素瘤脑转移完全消退。
Complete regression of a previously untreated melanoma brain metastasis with ipilimumab.
机构信息
Department of Dermatology, Hôpital Saint Louis Assistance Publique-Hôpitaux Paris, University of Paris 7, INSERM U976, Paris, France.
出版信息
Melanoma Res. 2010 Jun;20(3):247-50. doi: 10.1097/CMR.0b013e3283364a37.
Anecdotal cases of partial or complete responses have been reported after ipilimumab therapy for stage IV melanoma with brain metastasis treated earlier by surgery or radiosurgery. We report the first case of ipilimumab monotherapy resulting in durable complete remission of untreated, progressive brain metastases in a patient with stage IV melanoma. This case and earlier reports provide support for the further evaluation of ipilimumab in melanoma patients with brain metastasis.
有报道称，在接受手术或放射外科治疗的脑转移 IV 期黑色素瘤患者中，使用伊匹单抗治疗后，出现了部分或完全缓解的病例。我们报告了首例 IV 期黑色素瘤患者在未接受治疗的情况下，伊匹单抗单药治疗导致进展性脑转移完全缓解持久的病例。这一病例和之前的报告为进一步评估伊匹单抗在脑转移黑色素瘤患者中的作用提供了支持。
Zotero 插件