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土耳其 70 岁以上胃癌患者的手术治疗:术后早期结果和死亡风险因素。

Surgical treatment for gastric cancer in Turkish patients over age 70: early postoperative results and risk factors for mortality.

机构信息

Gastrointestinal Surgery, Türkiye Yüksek İhtisas Hospital, Ankara, Turkey.

出版信息

Langenbecks Arch Surg. 2010 Nov;395(8):1101-6. doi: 10.1007/s00423-010-0625-2. Epub 2010 Mar 10.

DOI:10.1007/s00423-010-0625-2
PMID:20217119
Abstract

PURPOSE

The aim of this study was to evaluate the effects of advanced age on early postoperative results and to investigate risk factors for mortality in Turkish gastric cancer patients.

METHODS

From 2002 to 2007, 549 patients who underwent gastrectomy for gastric cancer were divided into two groups as patients younger than 70 years and patients aged 70 years or older.

RESULTS

There were 387 patients in the younger group and 162 in the older group. Morbidity rates were similar (25.1% vs. 29.0%). Mortality was higher among the elderly patients (2.6% vs. 9.9%). Advanced age, albumin levels lower than 3 mg/dl, higher American Society of Anesthesiologists score, palliative resections and resection of two or more additional organs were independent risk factors for mortality.

CONCLUSION

Age alone should not preclude gastric resection in elderly patients. However, for patients with multiple risk factors, more limited surgery should be considered.

摘要

目的

本研究旨在评估高龄对胃癌患者术后早期结果的影响,并探讨其死亡的风险因素。

方法

2002 年至 2007 年间,549 例行胃癌切除术的患者被分为年龄小于 70 岁组和年龄等于或大于 70 岁组。

结果

年龄小于 70 岁组 387 例,年龄等于或大于 70 岁组 162 例。两组的发病率相似(25.1% vs. 29.0%)。老年患者死亡率更高(2.6% vs. 9.9%)。高龄、白蛋白水平低于 3mg/dl、美国麻醉医师协会评分较高、姑息性切除术和切除两个或更多其他器官是死亡的独立风险因素。

结论

年龄本身不应排除老年患者的胃切除术。然而,对于存在多种危险因素的患者,应考虑更有限的手术。

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本文引用的文献

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Surgical outcomes and survival after multiorgan resection for locally advanced gastric cancer.局部进展期胃癌多器官切除术后的手术结果与生存率
Am J Surg. 2009 Jul;198(1):25-30. doi: 10.1016/j.amjsurg.2008.06.031. Epub 2008 Sep 27.
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Is palliative resection necessary for gastric carcinoma patients?胃癌患者是否需要姑息性切除?
Langenbecks Arch Surg. 2008 Jan;393(1):31-5. doi: 10.1007/s00423-007-0206-1. Epub 2007 Jun 26.
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Impact of age on postoperative outcomes in 1118 gastric cancer patients undergoing surgical treatment.
口服超声造影在老年胃癌诊断中的价值。
World J Surg Oncol. 2018 Dec 7;16(1):233. doi: 10.1186/s12957-018-1527-y.
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年龄对1118例接受手术治疗的胃癌患者术后结局的影响。
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Surgical resection for gastric cancer in elderly patients: is there a difference in outcome?老年患者胃癌的手术切除:结局是否存在差异?
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Quality of complication reporting in the surgical literature.外科文献中并发症报告的质量。
Ann Surg. 2002 Jun;235(6):803-13. doi: 10.1097/00000658-200206000-00007.
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Achieving RO resection for locally advanced gastric cancer: is it worth the risk of multiorgan resection?实现局部进展期胃癌的R0切除:多器官切除的风险是否值得?
J Am Coll Surg. 2002 May;194(5):568-77. doi: 10.1016/s1072-7515(02)01116-x.
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Gastric cancer treatment guidelines in Japan.日本胃癌治疗指南。
Gastric Cancer. 2002;5(1):1-5. doi: 10.1007/s101200200000.
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Surgical mortality, survival, and quality of life after resection for gastric cancer in the elderly.老年胃癌切除术后的手术死亡率、生存率及生活质量
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