Hellström P A, Tammela T L, Kontturi M J, Lukkarinen O A
Department of Surgery, Oulu University Central Hospital, Finland.
Br J Urol. 1991 Mar;67(3):275-9. doi: 10.1111/j.1464-410x.1991.tb15134.x.
The clinical significance of the bladder cooling test as one part of a standard urodynamic examination was studied in 375 consecutive patients and 25 controls. Inability to perceive cold sensation in the bladder was common in cases of neurogenic lesions and present in nearly half of the patients with outlet obstruction, some with no urodynamic abnormalities and some of the normal subjects. The bladder contractions provoked by the test were clearly associated with detrusor overactivity, as in those patients with upper motor neuron lesions of motor urgency, but 27% of such patients showed no response. In 7 cases the iced water provoked detrusor contractions when cystometry showed no overactivity. This clinical series confirms that the cold receptors found recently in animal experiments are also present in the human urinary bladder. The bladder cooling test is not an alternative to cystometry, but its inclusion as an integral part of the urodynamic examination seems to be useful, especially in cases where there is also a need to study the sensibility of the bladder at the same time.
在375例连续患者和25例对照中研究了膀胱冷却试验作为标准尿动力学检查一部分的临床意义。在神经源性病变患者中，膀胱无法感知冷觉很常见，在近一半的出口梗阻患者中也存在，其中一些患者无尿动力学异常，部分正常受试者也存在此情况。该试验诱发的膀胱收缩明显与逼尿肌过度活动有关，如在上运动神经元病变导致运动性急迫性尿失禁的患者中，但27%的此类患者无反应。在7例患者中，膀胱测压显示无过度活动时，冰水诱发了逼尿肌收缩。该临床系列证实，最近在动物实验中发现的冷感受器在人类膀胱中也存在。膀胱冷却试验并非膀胱测压的替代方法，但将其纳入尿动力学检查的一个组成部分似乎是有用的，尤其是在同时需要研究膀胱敏感性的情况下。
