Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, National Naval Medical Center, Bethesda, Maryland, USA.
Clin Infect Dis. 2010 Apr 15;50(8):1187-91. doi: 10.1086/651421.
Sixty-two human immunodeficiency virus (HIV) controllers (6 elite and 56 viremic controllers) in the US Military Department of Defense HIV Natural History Study cohort initiated highly active antiretroviral therapy (HAART) and achieved statistically significant mean CD4 cell count increases, although the gains were lower than those in treated noncontrollers. HIV controllers experienced CD4 cell count reconstitution with HAART regardless of pretherapy viral load, including patients with undetectable viral loads at HAART initiation.
62 名人类免疫缺陷病毒 (HIV) 控制器（6 名精英控制器和 56 名病毒控制器）在美国国防部 HIV 自然史研究队列中开始接受高效抗逆转录病毒治疗 (HAART)，并实现了具有统计学意义的平均 CD4 细胞计数增加，尽管这些增加低于接受治疗的非控制器。HIV 控制器在接受 HAART 治疗后经历了 CD4 细胞计数的重建，无论治疗前的病毒载量如何，包括在 HAART 开始时病毒载量无法检测到的患者。
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