Schippers E, Hölscher A H, Bollschweiler E, Siewert J R
Department of Surgery, Klinikum rechts der Isar Technical University, Munich, F.R.G.
Dig Dis Sci. 1991 May;36(5):621-6. doi: 10.1007/BF01297029.
Gastrointestinal mechanical activity was studied in 13 patients after different surgical procedures in a fasted and fed state and after pharmacological stimulation. Mechanical activity was recorded by means of a multi-pressure sensor probe placed intraoperatively into the jejunum. Abdominal surgery abolished normal motility only for a short period of time. The time for the reappearance of regular recurring activity fronts varied with the type of the surgical procedure from 3 hr after cholecystectomy to the sixth postoperative day after colon resection. The fed pattern occurred after the first postoperative interdigestive motor complex in all experiments. Stimulation was observed with ceruletide, which induced contractile activity in the small intestine during postoperative ileus. No coordinated caudad propagating activity was observed. The postoperative interdigestive motor complex did not correlate in time with the first passage of flatus and stool in our patients. Thus, the restoration of motility in the small intestine did not coincide with the clinical relief from the so-called "physiological" postoperative ileus.
对13例接受不同外科手术的患者在禁食、进食状态下以及药物刺激后进行了胃肠机械活动研究。通过术中置于空肠的多压力传感器探头记录机械活动。腹部手术仅在短时间内消除了正常的蠕动。规律复发性活动波阵面重新出现的时间因手术类型而异，从胆囊切除术后3小时到结肠切除术后第六天。在所有实验中，进食模式在术后第一个消化间期运动复合波之后出现。观察到蛙皮素刺激，其在术后肠梗阻期间诱导小肠收缩活动。未观察到协调的向尾端传播活动。在我们的患者中，术后消化间期运动复合波与首次排气和排便在时间上不相关。因此，小肠蠕动的恢复与所谓“生理性”术后肠梗阻的临床缓解并不一致。
