α-肾上腺素能对血压的支持作用存在性别差异。
Sex differences in alpha-adrenergic support of blood pressure.
机构信息
Department of Anesthesiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA.
出版信息
Clin Auton Res. 2010 Aug;20(4):271-5. doi: 10.1007/s10286-010-0061-y. Epub 2010 Mar 11.
Abstract
We tested whether the inter-individual variability in alpha-adrenergic support of blood pressure plays a critical role in the sex differences in tonic support of blood pressure by the autonomic nervous system. Blockade of the alpha-adrenergic receptors was achieved via phentolamine and showed a smaller (P < 0.05) decrease in blood pressure in women compared to men, implying that alpha-adrenergic support of blood pressure is less in women than in men.
摘要
我们测试了个体间α-肾上腺素能对血压的支持的变异性是否在自主神经系统对血压的紧张性支持的性别差异中起关键作用。通过酚妥拉明阻断α-肾上腺素能受体，结果显示女性的血压下降幅度较小（P<0.05），这表明女性的血压受α-肾上腺素能的支持比男性少。
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