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血栓弹力图止血分析仪在检测手术(无论是否使用间歇性气动压迫)后高凝状态中的作用

Role of thrombelastograph haemostasis analyser in detection of hypercoagulability following surgery with and without use of intermittent pneumatic compression.

作者信息

Lee B Y, Butler G, Al-Waili N, Herz B, Savino J, Delguercio L R, Garcia J, Al-Waili A, Al-Waili D

机构信息

Department of Surgery, New York Medical College, Valhalla, New York, NY, USA.

出版信息

J Med Eng Technol. 2010 Apr;34(3):166-71. doi: 10.3109/03091900903402071.

DOI:10.3109/03091900903402071
PMID:20222835
Abstract

The effect of using intermittent pneumatic compression on incidence of postoperative thromboembolic events was studied, and hypercoagulability following various kinds of surgery with or without use of intermittent pneumatic compression was evaluated with the use of a thrombelastograph. The study included 317 male patients undergoing various surgical procedures; 193 patients used intermittent pneumatic compression after surgery and 124 did not use intermittent pneumatic compression. Their ages ranged between 52 and 75 years. Thrombelastograph was used to detect hypercoagulability. Results showed that in patients using intermittent pneumatic compression, 67% of the hip surgery patients had hypercoagulability one to three days postoperatively, as did 34% having major thoracic or abdominal procedures and 18% in the remaining general surgery. Of 18 hip surgery patients who did not use intermittent pneumatic compression, 10 sustained thromboembolic complications following operation. Three deaths resulted from pulmonary embolism. For the remaining 106 patients who did not use intermittent pneumatic compression, seven patients manifested Deep venous thrombosis (DVT) and pulmonary embolism, and three deaths resulted from pulmonary embolism. There was no incident of thromboembolic complications for the 24 patients with hip surgery who used the intermittent pneumatic compression. There were no complications following various surgical procedures in the 169 patients who used intermittent pneumatic compression. It might be concluded that the thrombelastograph is useful to detect hypercoagulability postoperatively, and intermittent pneumatic compression is useful for thromboembolic prophylaxis.

摘要

研究了使用间歇性气动压迫对术后血栓栓塞事件发生率的影响,并使用血栓弹性描记仪评估了在各种手术中使用或不使用间歇性气动压迫后的高凝状态。该研究纳入了317例接受各种外科手术的男性患者;193例患者术后使用间歇性气动压迫,124例未使用间歇性气动压迫。他们的年龄在52岁至75岁之间。使用血栓弹性描记仪检测高凝状态。结果显示,在使用间歇性气动压迫的患者中,67%的髋关节手术患者术后1至3天出现高凝状态,接受大型胸腹部手术的患者中有34%出现高凝状态,其余普通外科手术患者中有18%出现高凝状态。在18例未使用间歇性气动压迫的髋关节手术患者中,10例术后出现血栓栓塞并发症。3例死于肺栓塞。在其余106例未使用间歇性气动压迫的患者中,7例出现深静脉血栓形成(DVT)和肺栓塞,3例死于肺栓塞。24例使用间歇性气动压迫的髋关节手术患者未发生血栓栓塞并发症。169例使用间歇性气动压迫的患者在各种外科手术后均未出现并发症。可以得出结论,血栓弹性描记仪有助于检测术后高凝状态,间歇性气动压迫对预防血栓栓塞有效。

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