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乳房切除术后即刻乳房重建:长期前景如何?

Immediate breast reconstruction after mastectomy: what are the long-term prospects?

作者信息

Rusby Jennifer E, Waters Ruth A, Nightingale Peter G, England David W

机构信息

University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital, Birmingham B15 2TH, UK.

出版信息

Ann R Coll Surg Engl. 2010 Apr;92(3):193-7. doi: 10.1308/003588410X12628812458770. Epub 2010 Mar 10.

Abstract

INTRODUCTION

Immediate breast reconstruction after mastectomy has known psychological and financial advantages but it is difficult to compare the outcome of various methods of reconstruction. Re-operation rates are an objective measure of surgical intervention required to attain and maintain acceptable cosmesis.

PATIENTS AND METHODS

A series of 95 patients (110 immediate reconstructions) was analysed for number of re-operations required within 5 years of initial surgery, magnitude of procedures, 'survival' of the reconstruction and effect of radiotherapy.

RESULTS

Although more intervention was seen in patients with implant-based reconstruction and the time-course over which autologous and implant-based reconstructions fail is different these did not reach statistical significance. Radiotherapy has a significant effect on failure of implant-based reconstruction.

CONCLUSIONS

Long-term, large studies of immediate reconstruction are required to assess adequately the impact of type of reconstruction on re-operation rates. The National Mastectomy and Breast Reconstruction Audit is ideally placed to provide answers to remaining questions about longevity of immediate breast reconstruction and the effect that late failure has on patient satisfaction.

摘要

引言

乳房切除术后立即进行乳房重建具有心理和经济方面的已知优势,但各种重建方法的效果很难进行比较。再次手术率是衡量为实现并保持可接受的美观效果所需外科干预的一个客观指标。

患者与方法

对95例患者(110次即刻重建)进行了分析,统计初次手术后5年内所需的再次手术次数、手术规模、重建的“留存率”以及放疗的影响。

结果

尽管基于植入物的重建患者需要更多干预,且自体组织重建和基于植入物的重建失败的时间进程有所不同,但这些差异未达到统计学意义。放疗对基于植入物的重建失败有显著影响。

结论

需要开展关于即刻重建的长期大型研究,以充分评估重建类型对再次手术率的影响。国家乳房切除术和乳房重建审计最适合回答有关即刻乳房重建的持久性以及晚期失败对患者满意度的影响等剩余问题。

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