Department of Urology, University of Texas, Southwestern Medical Center and Children's Medical Center, Dallas, Texas, USA.
Urology. 2010 Jul;76(1):175-9. doi: 10.1016/j.urology.2009.09.092. Epub 2010 Mar 12.
To investigate whether an initial ultrasound (US) adequately identifies those patients who need further investigation and possibly intervention while decreasing instrumentation and radiation exposure. The recommended imaging after pediatric pyeloplasty has included intravenous pyelography, radionucleotide renography, and ultrasound US.
We retrospectively reviewed pediatric open pyeloplasty cases performed between 1999 and 2007. Of 116 patients reviewed, 49 met the inclusion criteria of unilateral pyeloplasty with pre- and postoperative US and mercaptoacetyltriglycine (MAG-3). Hydronephrosis was judged by anterior posterior pelvic diameter and caliectasis. Change in renal function on MAG-3 was defined as increase or decrease in function >5%.
Of 49 patients, 42 (85.7%) showed improved or stable hydronephrosis postoperatively and 7 (14.3%) showed increased hydronephrosis. Forty-six (93.8%) patients had either improved or stable renal function. Of 42 patients with stable or improved hydronephrosis, 41 (97.6%) also had stable or improved function. Comparatively, of 7 patients with increasing hydronephrosis, 2 (28.6%) showed deteriorated renal function, P = .05.
Postpediatric pyeloplasty imaging should aim to identify those who require further intervention. Our data demonstrate that at-risk patients can be identified with a sentinel US and selectively determine who needs further MAG-3 investigation. This should increase compliance while decreasing costs, instrumentation, and radiation exposure.
探讨初始超声(US)是否能充分识别出那些需要进一步检查和可能干预的患者,同时减少器械和辐射暴露。推荐的小儿肾盂成形术后影像学检查包括静脉肾盂造影、放射性核素肾图和超声 US。
我们回顾性分析了 1999 年至 2007 年间行开放肾盂成形术的小儿病例。在 116 例患者中,49 例符合单侧肾盂成形术的纳入标准,包括术前和术后的 US 和巯基乙酰三甘氨酸(MAG-3)。肾盂积水通过前后骨盆直径和肾盏扩张来判断。MAG-3 上肾功能的变化定义为功能增加或减少>5%。
在 49 例患者中,42 例(85.7%)术后肾盂积水改善或稳定,7 例(14.3%)肾盂积水加重。46 例(93.8%)患者的肾功能有改善或稳定。在 42 例肾盂积水稳定或改善的患者中,41 例(97.6%)肾功能也稳定或改善。相比之下,在 7 例肾盂积水加重的患者中,有 2 例(28.6%)肾功能恶化,P=0.05。
小儿肾盂成形术后的影像学检查应旨在识别需要进一步干预的患者。我们的数据表明,通过哨兵 US 可以识别出高危患者,并选择性地确定哪些患者需要进一步的 MAG-3 检查。这应该可以提高依从性,同时降低成本、器械和辐射暴露。