Hofmann A F, Schteingart C D, vanSonnenberg E, Esch O, Zakko S F
Department of Medicine, University of California, San Diego, La Jolla.
Gastroenterol Clin North Am. 1991 Mar;20(1):183-99.
Contact dissolution of cholesterol gallstones with organic solvents is emerging as a rapid, safe, alternative treatment for symptomatic cholesterol gallbladder stones. Placement of a percutaneous transhepatic catheter into the gallbladder is a rapid and safe technique. The availability of safe, effective cholesterol solvents and solvent transfer devices means that cholesterol gallbladder stones can be eliminated rapidly and safely by CDOS, without the risk of general anesthesia or surgical dissection of the gallbladder bed. Patients with single gallstones are better candidates for CDOS than are patients with multiple gallstones because recurrence after dissolution is less common. Contact dissolution may well be judged the treatment of choice by the medical-surgical gallstone management team in some patients.
胆固醇性胆结石与有机溶剂的接触溶解正成为一种快速、安全的有症状胆固醇性胆囊结石替代治疗方法。经皮经肝将导管置入胆囊是一种快速且安全的技术。安全、有效的胆固醇溶剂和溶剂输送装置的出现意味着胆固醇性胆囊结石可通过接触溶解法快速、安全地消除,而无需全身麻醉或对胆囊床进行手术解剖。与有多个胆结石的患者相比,单个胆结石患者更适合接受接触溶解法治疗,因为溶解后复发情况较少见。在某些患者中,接触溶解法很可能被外科胆结石治疗团队判定为首选治疗方法。