Ji Cheol, Ahn Jae-Geun, Huh Han-Yong, Park Chun-Kun
Department of Neurosurgery, St. Paul's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea.
J Korean Neurosurg Soc. 2010 Feb;47(2):137-9. doi: 10.3340/jkns.2010.47.2.137. Epub 2010 Feb 28.
A subarachnoid hemorrhage (SAH) associated with negative finding on four-vessel angiography is seen in 5 to 30% of patients with intracranial SAH. A previously silent lesion in the spinal canal may be responsible for the angiographically negative finding for cause of intracranial SAH. We report a case of upper cervical (C1-2) intradural schwannoma presenting with acute intracranial SAH. Repeated cerebral angiographic studies were negative, but cervical magnetic resonance imaging study and tissue pathology revealed a intradural-extramedullary schwannoma in C1-2 level. This case illustrates the importance of a high index of clinical suspicion for spinal disease in angiographically negative intracranial SAH patients.
在颅内蛛网膜下腔出血(SAH)患者中,5%至30%的患者在四血管造影检查中呈现阴性结果。椎管内先前无症状的病变可能是颅内SAH血管造影呈阴性结果的原因。我们报告一例表现为急性颅内SAH的上颈椎(C1-2)硬膜内神经鞘瘤病例。多次脑血管造影检查结果均为阴性,但颈椎磁共振成像检查和组织病理学检查显示C1-2水平存在硬膜内髓外神经鞘瘤。该病例说明了对于血管造影呈阴性的颅内SAH患者,高度临床怀疑脊髓疾病的重要性。