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脊髓神经鞘瘤伴脊髓内血肿:一例报告并文献复习

Spinal schwannoma presenting with intraspinal hematoma: a case report and review of the literature.

作者信息

Shen Zhe, Chen Haoyang, Wang Haosheng, Wang Yaoqi, Li Tao

机构信息

Department of Neurosurgery, The First Affiliated Hospital of Henan University of Science and Technology, 24 JingHua Road, Luoyang, 471000, Henan, China.

出版信息

J Med Case Rep. 2024 Dec 21;18(1):633. doi: 10.1186/s13256-024-04968-4.

DOI:10.1186/s13256-024-04968-4
PMID:39709503
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11662569/
Abstract

BACKGROUND

Spinal schwannomas presenting with an intraspinal hematoma or subarachnoid hemorrhage are extremely rare, and patients often have severe spinal cord compression symptoms. However, the mechanism underlying the bleeding remains unclear.

CASE PRESENTATION

We present the case of a 53-year-old Chinese female diagnosed with a T12 schwannoma accompanied by an intratumoral hematoma. The patient suddenly experienced unbearable pain in the lower limbs. An emergency operation was necessary, and during surgery, we resected a tumor and evacuated a hematoma. We found a spinal nerve root fracture, intratumoral congestion, tumor capsule rupture, and bleeding. Pathological analysis indicated a schwannoma.

CONCLUSION

Injury to the nerve roots and vessels during motion, nerve root torsion, twisting, venous obstruction, tumor congestion, swelling, and capsule rupture are important processes in spinal schwannoma hemorrhage. Early diagnosis and proactive surgery are key points for treatment.

摘要

背景

伴有脊髓内血肿或蛛网膜下腔出血的脊髓神经鞘瘤极为罕见,患者常出现严重的脊髓压迫症状。然而,出血的潜在机制尚不清楚。

病例报告

我们报告一例53岁中国女性,诊断为T12神经鞘瘤并伴有瘤内血肿。患者突然出现下肢难以忍受的疼痛。急诊手术是必要的,手术中我们切除了肿瘤并清除了血肿。我们发现脊神经根断裂、瘤内充血、肿瘤包膜破裂和出血。病理分析显示为神经鞘瘤。

结论

运动过程中神经根和血管的损伤、神经根扭转、扭曲、静脉阻塞、肿瘤充血、肿胀和包膜破裂是脊髓神经鞘瘤出血的重要过程。早期诊断和积极手术是治疗的关键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d672/11662569/443c3bd75413/13256_2024_4968_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d672/11662569/d6c19c05c193/13256_2024_4968_Fig1_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d672/11662569/71498ad7d898/13256_2024_4968_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d672/11662569/ef6c8e4832bf/13256_2024_4968_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d672/11662569/3b4a4bb72978/13256_2024_4968_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d672/11662569/6cba9146b34f/13256_2024_4968_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d672/11662569/443c3bd75413/13256_2024_4968_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d672/11662569/d6c19c05c193/13256_2024_4968_Fig1_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d672/11662569/71498ad7d898/13256_2024_4968_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d672/11662569/ef6c8e4832bf/13256_2024_4968_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d672/11662569/3b4a4bb72978/13256_2024_4968_Fig6_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d672/11662569/443c3bd75413/13256_2024_4968_Fig8_HTML.jpg

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本文引用的文献

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Spinal intradural schwannoma presenting with acute subarachnoid hemorrhage: a case report and review of published reports.以急性蛛网膜下腔出血为表现的脊髓硬脊膜内 schwann 瘤:病例报告及文献复习。
J Int Med Res. 2022 Jan;50(1):3000605221075814. doi: 10.1177/03000605221075814.
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Hemorrhage in long segment cervical schwannoma; case report and literature review.长节段颈段神经鞘瘤出血:病例报告及文献复习
Surg Neurol Int. 2020 Dec 29;11:476. doi: 10.25259/SNI_833_2020. eCollection 2020.
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Spinal schwannoma causes acute subarachnoid haemorrhage: A case report and literature review.
脊髓神经鞘瘤导致急性蛛网膜下腔出血:病例报告及文献复习。
Neurochirurgie. 2021 Sep;67(5):495-499. doi: 10.1016/j.neuchi.2020.12.002. Epub 2021 Jan 12.
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Intralesional and subarachnoid bleeding of a spinal schwannoma presenting with acute cauda equina syndrome.表现为急性马尾综合征的脊髓神经鞘瘤的瘤内及蛛网膜下腔出血。
BMJ Case Rep. 2019 Jul 12;12(7):e229251. doi: 10.1136/bcr-2019-229251.
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A Rare Case of Spinal Schwannoma in a Child Presenting with Subarachnoid Hemorrhage: A Case Report with Review of Literature.一名儿童脊髓神经鞘瘤伴蛛网膜下腔出血的罕见病例:病例报告及文献复习
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Differentiation between intraspinal schwannoma and meningioma by MR characteristics and clinic features.通过磁共振特征和临床特征鉴别椎管内神经鞘瘤和脑膜瘤。
Radiol Med. 2019 Jun;124(6):510-521. doi: 10.1007/s11547-019-00988-z. Epub 2019 Jan 25.
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Spine J. 2015 Dec 1;15(12):e17-8. doi: 10.1016/j.spinee.2015.07.424. Epub 2015 Jul 17.
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